Large-scale analysis of pseudogenes in the human genome

@article{citeulike:1572696, abstract = {Pseudogenes are considered as genomic fossils: disabled copies of functional genes that were once active in the ancient genome. Recently, whole-genome computational approaches have revealed thousands of pseudogenes in the genomes of the human and other eukaryotes. Identification of these pseudogenes can improve the accuracy of gene annotation. It also offers new insight on the evolutionary history and the stability of the genome as a whole.}, author = {Zhang, Zhaolei and Gerstein, Mark }, citeulike-article-id = {1572696}, doi = {10.1016/j.gde.2004.06.003}, journal = {Current Opinion in Genetics \& Development}, keywords = {genomics, pseudogene}, month = {August}, number = {4}, pages = {328--335}, posted-at = {2007-08-17 17:29:57}, priority = {2}, title = {Large-scale analysis of pseudogenes in the human genome}, url = {http://dx.doi.org/10.1016/j.gde.2004.06.003}, volume = {14}, year = {2004} }

TY - JOUR ID - citeulike:1572696 L3 - citeulike-article-id:1572696 TI - Large-scale analysis of pseudogenes in the human genome JF - Current Opinion in Genetics & Development VL - 14 IS - 4 SP - 328 EP - 335 N2 - Pseudogenes are considered as genomic fossils: disabled copies of functional genes that were once active in the ancient genome. Recently, whole-genome computational approaches have revealed thousands of pseudogenes in the genomes of the human and other eukaryotes. Identification of these pseudogenes can improve the accuracy of gene annotation. It also offers new insight on the evolutionary history and the stability of the genome as a whole. KW - genomics KW - pseudogene AU - Zhang, Zhaolei AU - Gerstein, Mark PY - 2004/08// UR - http://dx.doi.org/10.1016/j.gde.2004.06.003 ER -