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A genetic algorithm for the detection of new cis-regulatory modules in sets of coregulated genes.

by: S Aerts, P Van Loo, Y Moreau, B De Moor
Bioinformatics, Vol. 20, No. 12. (12 August 2004), pp. 1974-1976.


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SUMMARY: The implementation of a genetic algorithm is described that provides a fast method of searching for the optimal combination of transcription factor binding sites in a set of regulatory sequences. AVAILABILITY: The algorithm can be used transparently as a web service from within the Toucan software. Toucan can be accessed at http://www.esat.kuleuven.ac.be/~saerts/software/toucan.php. A standalone version of the software is available upon request.


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