Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles

by: AD Dinsmore, Ming F Hsu, MG Nikolaides, Manuel Marquez, AR Bausch, DA Weitz

Science, Vol. 298, No. 5595. (1 November 2002), pp. 1006-1009.

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Abstract

We present an approach to fabricate solid capsules with precise control of size, permeability, mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of colloidal particles onto the interface of emulsion droplets. After the particles are locked together to form elastic shells, the emulsion droplets are transferred to a fresh continuous-phase fluid that is the same as that inside the droplets. The resultant structures, which we call "colloidosomes," are hollow, elastic shells whose permeability and elasticity can be precisely controlled. The generality and robustness of these structures and their potential for cellular immunoisolation are demonstrated by the use of a variety of solvents, particles, and contents.

@article{dinsmore02, abstract = {We present an approach to fabricate solid capsules with precise control of size, permeability, mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of colloidal particles onto the interface of emulsion droplets. After the particles are locked together to form elastic shells, the emulsion droplets are transferred to a fresh continuous-phase fluid that is the same as that inside the droplets. The resultant structures, which we call "colloidosomes," are hollow, elastic shells whose permeability and elasticity can be precisely controlled. The generality and robustness of these structures and their potential for cellular immunoisolation are demonstrated by the use of a variety of solvents, particles, and contents.}, author = {Dinsmore, A. D. and Hsu, Ming F. and Nikolaides, M. G. and Marquez, Manuel and Bausch, A. R. and Weitz, D. A. }, citeulike-article-id = {1210848}, doi = {10.1126/science.1074868}, journal = {Science}, keywords = {journal-club, self-assembly, vesicles}, month = {November}, number = {5595}, pages = {1006--1009}, posted-at = {2007-09-27 05:30:38}, priority = {0}, title = {Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles}, url = {http://dx.doi.org/10.1126/science.1074868}, volume = {298}, year = {2002} }

RIS record

TY - JOUR ID - dinsmore02 L3 - citeulike-article-id:1210848 TI - Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles JF - Science VL - 298 IS - 5595 SP - 1006 EP - 1009 N2 - We present an approach to fabricate solid capsules with precise control of size, permeability, mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of colloidal particles onto the interface of emulsion droplets. After the particles are locked together to form elastic shells, the emulsion droplets are transferred to a fresh continuous-phase fluid that is the same as that inside the droplets. The resultant structures, which we call "colloidosomes," are hollow, elastic shells whose permeability and elasticity can be precisely controlled. The generality and robustness of these structures and their potential for cellular immunoisolation are demonstrated by the use of a variety of solvents, particles, and contents. KW - journal-club KW - self-assembly KW - vesicles AU - Dinsmore, AD AU - Hsu, Ming AU - Nikolaides, MG AU - Marquez, Manuel AU - Bausch, AR AU - Weitz, DA PY - 2002/11/01/ UR - http://dx.doi.org/10.1126/science.1074868 ER -

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