Functional variation and evolution of non-coding DNA

@article{citeulike:975260, abstract = {The focus of large genomic studies has shifted from only looking at genes and protein-coding sequences to exploring the full set of elements in each genome. The explosion of comparative sequencing data has led to an increase in methodologies, approaches and ideas on how to analyze the unknown fraction of the genome, namely the non-protein-coding fraction. The main issues relate to the discovery, evolutionary analysis and natural variation of non-coding DNA, and the parameters that prevent us from fully understanding the properties of non-coding DNA.}, author = {Bird, Christine P. and Stranger, Barbara E. and Dermitzakis, Emmanouil T. }, booktitle = {Genomes and evolution}, citeulike-article-id = {975260}, comment = {Hypothesize what might have been if non-coding function of DNA had been discovered first.}, doi = {http://dx.doi.org/10.1016/j.gde.2006.10.003}, journal = {Current Opinion in Genetics \& Development}, keywords = {cne, evolution, non-coding}, month = {December}, number = {6}, pages = {559--564}, posted-at = {2007-03-10 16:21:09}, priority = {0}, title = {Functional variation and evolution of non-coding DNA}, url = {http://dx.doi.org/10.1016/j.gde.2006.10.003}, volume = {16}, year = {2006} }

TY - JOUR ID - citeulike:975260 L3 - citeulike-article-id:975260 TI - Functional variation and evolution of non-coding DNA T2 - Genomes and evolution JF - Current Opinion in Genetics & Development VL - 16 IS - 6 SP - 559 EP - 564 N2 - The focus of large genomic studies has shifted from only looking at genes and protein-coding sequences to exploring the full set of elements in each genome. The explosion of comparative sequencing data has led to an increase in methodologies, approaches and ideas on how to analyze the unknown fraction of the genome, namely the non-protein-coding fraction. The main issues relate to the discovery, evolutionary analysis and natural variation of non-coding DNA, and the parameters that prevent us from fully understanding the properties of non-coding DNA. KW - cne KW - evolution KW - non-coding N1 - Hypothesize what might have been if non-coding function of DNA had been discovered first. AU - Bird, Christine AU - Stranger, Barbara AU - Dermitzakis, Emmanouil PY - 2006/12// UR - http://dx.doi.org/10.1016/j.gde.2006.10.003 ER -