One Dimensional Boundaries for DNA Tile Self-Assembly

@incollection{citeulike:2350873, abstract = {In this paper we report the design and synthesis of DNA molecules (referred to as DNA tiles) with specific binding interactions that guide self-assembly to make one-dimensional assemblies shaped as lines, V’s and X’s. These DNA tile assemblies have been visualized by atomic force microscopy. The highly-variable distribution of shapes – e.g., the length of the arms of X-shaped assemblies – gives us insight into how the assembly process is occurring. Using stochastic models that simulate addition and dissociation of each type of DNA tile, as well as simplified models that more cleanly examine the generic phenomena, we dissect the contribution of accretion vs aggregation, reversible vs irreversible and seeded vs unseeded assumptions for describing the growth processes. The results suggest strategies for controlling self-assembly to make more uniformly-shaped assemblies.}, author = {Schulman, Rebecca and Lee, Shaun and Papadakis, Nick and Winfree, Erik }, citeulike-article-id = {2350873}, comment = {talks about variable length sticky ends}, journal = {DNA Computing}, keywords = {boundaries, self-assembly}, pages = {108--125}, posted-at = {2008-02-08 00:43:27}, priority = {2}, title = {One Dimensional Boundaries for DNA Tile Self-Assembly}, url = {http://www.springerlink.com/content/85jjmdwxphgjdh0k }, year = {2004} }

TY - CHAP ID - citeulike:2350873 L3 - citeulike-article-id:2350873 TI - One Dimensional Boundaries for DNA Tile Self-Assembly JF - DNA Computing SP - 108 EP - 125 N2 - In this paper we report the design and synthesis of DNA molecules (referred to as DNA tiles) with specific binding interactions that guide self-assembly to make one-dimensional assemblies shaped as lines, V’s and X’s. These DNA tile assemblies have been visualized by atomic force microscopy. The highly-variable distribution of shapes – e.g., the length of the arms of X-shaped assemblies – gives us insight into how the assembly process is occurring. Using stochastic models that simulate addition and dissociation of each type of DNA tile, as well as simplified models that more cleanly examine the generic phenomena, we dissect the contribution of accretion vs aggregation, reversible vs irreversible and seeded vs unseeded assumptions for describing the growth processes. The results suggest strategies for controlling self-assembly to make more uniformly-shaped assemblies. KW - boundaries KW - self-assembly N1 - talks about variable length sticky ends AU - Schulman, Rebecca AU - Lee, Shaun AU - Papadakis, Nick AU - Winfree, Erik PY - 2004/// UR - http://www.springerlink.com/content/85jjmdwxphgjdh0k ER -