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Agent-Specific Responses in the Cingulate Cortex During Economic Exchanges

by: Damon Tomlin, Amin M Kayali, Brooks King-Casas, Cedric Anen, Colin F Camerer, Steven R Quartz, Read P Montague
Science, Vol. 312, No. 5776. (19 May 2006), pp. 1047-1050.


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Interactions with other responsive agents lie at the core of all social exchange. During a social exchange with a partner, one fundamental variable that must be computed correctly is who gets credit for a shared outcome; this assignment is crucial for deciding on an optimal level of cooperation that avoids simple exploitation. We carried out an iterated, two-person economic exchange and made simultaneous hemodynamic measurements from each player's brain. These joint measurements revealed agent-specific responses in the social domain ("me" and "not me") arranged in a systematic spatial pattern along the cingulate cortex. This systematic response pattern did not depend on metrical aspects of the exchange, and it disappeared completely in the absence of a responding partner. 10.1126/science.1125596


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