Two case studies illustrating how relatively selective hippocampal lesions in humans can have quite different effects on memory.

@article{citeulike:2663816, abstract = {Two patients, with magnetic resonance imaging (MRI)-confirmed relatively selective hippocampal damage, showed distinct patterns of performance on tests of recall, item recognition, and associative recognition. Patient AC showed a mean bilateral volume reduction of the hippocampus of 28\%, but displayed no memory deficit. Both recall and recognition memory were unimpaired. In contrast, patient PR, who showed a mean bilateral hippocampal volume reduction of 59\%, was more consistently impaired on recall than recognition tests, although his recognition scores were highly variable. Patients AC and PR illustrate how variable the memory deficit following seemingly selective hippocampal damage can be in humans. They highlight the need for more sophisticated imaging in future studies if the human hippocampus' role in memory is to be fully identified. (c) 2008 Wiley-Liss, Inc.}, address = {School of Psychology, University of Liverpool, Liverpool, United Kingdom.}, author = {Holdstock, J S S. and Parslow, D M M. and Morris, R G G. and Fleminger, S and Abrahams, S and Denby, C and Montaldi, D and Mayes, A R R. }, citeulike-article-id = {2663816}, doi = {10.1002/hipo.20427}, issn = {1098-1063}, journal = {Hippocampus}, keywords = {general, hippocampus, memory, wow}, month = {April}, posted-at = {2008-04-13 16:02:33}, priority = {4}, title = {Two case studies illustrating how relatively selective hippocampal lesions in humans can have quite different effects on memory.}, url = {http://dx.doi.org/10.1002/hipo.20427}, year = {2008} }

TY - JOUR ID - citeulike:2663816 L3 - citeulike-article-id:2663816 TI - Two case studies illustrating how relatively selective hippocampal lesions in humans can have quite different effects on memory. JF - Hippocampus AD - School of Psychology, University of Liverpool, Liverpool, United Kingdom. SN - 1098-1063 N2 - Two patients, with magnetic resonance imaging (MRI)-confirmed relatively selective hippocampal damage, showed distinct patterns of performance on tests of recall, item recognition, and associative recognition. Patient AC showed a mean bilateral volume reduction of the hippocampus of 28%, but displayed no memory deficit. Both recall and recognition memory were unimpaired. In contrast, patient PR, who showed a mean bilateral hippocampal volume reduction of 59%, was more consistently impaired on recall than recognition tests, although his recognition scores were highly variable. Patients AC and PR illustrate how variable the memory deficit following seemingly selective hippocampal damage can be in humans. They highlight the need for more sophisticated imaging in future studies if the human hippocampus' role in memory is to be fully identified. (c) 2008 Wiley-Liss, Inc. KW - general KW - hippocampus KW - memory KW - wow AU - Holdstock, J S AU - Parslow, D M AU - Morris, R G AU - Fleminger, S AU - Abrahams, S AU - Denby, C AU - Montaldi, D AU - Mayes, A R PY - 2008/04/08/ UR - http://dx.doi.org/10.1002/hipo.20427 ER -