Screening for insecticide overexposure under field conditions: a reevaluation of the tintometric cholinesterase kit.

@article{citeulike:2702559, abstract = {A semiquantitative tintometric field kit has been used in the developing world for almost 30 years to measure whole blood cholinesterase levels in persons exposed to organophosphate pesticides. The validity of this screening kit was evaluated among 79 workers heavily exposed to organophosphates by comparison with a reference assay for erythrocyte cholinesterase. Overall correlation between the two methods was good. However, either sensitivity or specificity of the tintometric kit was less than 75\% for each of the three tintometric categories commonly used to define the limit of normal. Because baseline erythrocyte cholinesterase levels were not available for this population, the true sensitivity and specificity of the tintometric assay may be even lower.}, address = {Division of Occupational and Environmental Medicine, Mount Sinai School of Medicine, New York, NY 10029.}, author = {McConnell, R. and Magnotti, R. }, citeulike-article-id = {2702559}, comment = {basic info on pesticide poisonings (numbers as of 1994)}, issn = {0090-0036}, journal = {American journal of public health}, keywords = {pesticides}, month = {March}, number = {3}, pages = {479--481}, posted-at = {2008-04-22 18:12:59}, priority = {2}, title = {Screening for insecticide overexposure under field conditions: a reevaluation of the tintometric cholinesterase kit.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/8129072}, volume = {84}, year = {1994} }

TY - JOUR ID - citeulike:2702559 L3 - citeulike-article-id:2702559 TI - Screening for insecticide overexposure under field conditions: a reevaluation of the tintometric cholinesterase kit. JF - American journal of public health VL - 84 IS - 3 SP - 479 EP - 481 AD - Division of Occupational and Environmental Medicine, Mount Sinai School of Medicine, New York, NY 10029. SN - 0090-0036 N2 - A semiquantitative tintometric field kit has been used in the developing world for almost 30 years to measure whole blood cholinesterase levels in persons exposed to organophosphate pesticides. The validity of this screening kit was evaluated among 79 workers heavily exposed to organophosphates by comparison with a reference assay for erythrocyte cholinesterase. Overall correlation between the two methods was good. However, either sensitivity or specificity of the tintometric kit was less than 75% for each of the three tintometric categories commonly used to define the limit of normal. Because baseline erythrocyte cholinesterase levels were not available for this population, the true sensitivity and specificity of the tintometric assay may be even lower. KW - pesticides N1 - basic info on pesticide poisonings (numbers as of 1994) AU - McConnell, R AU - Magnotti, R PY - 1994/03// UR - http://view.ncbi.nlm.nih.gov/pubmed/8129072 ER -