A tour of structural genomics.

by: SE Brenner

Nat Rev Genet, Vol. 2, No. 10. (October 2001), pp. 801-809.

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Abstract

Structural genomics projects aim to provide an experimental or computational three-dimensional model structure for all of the tractable macromolecules that are encoded by complete genomes. To this end, pilot centres worldwide are now exploring the feasibility of large-scale structure determination. Their experimental structures and computational models are expected to yield insight into the molecular function and mechanism of thousands of proteins. The pervasiveness of this information is likely to change the use of structure in molecular biology and biochemistry.

@article{citeulike:447073, abstract = {Structural genomics projects aim to provide an experimental or computational three-dimensional model structure for all of the tractable macromolecules that are encoded by complete genomes. To this end, pilot centres worldwide are now exploring the feasibility of large-scale structure determination. Their experimental structures and computational models are expected to yield insight into the molecular function and mechanism of thousands of proteins. The pervasiveness of this information is likely to change the use of structure in molecular biology and biochemistry.}, address = {Department of Plant and Microbial Biology, University of California, 461A Koshland Hall, Berkeley, California 94720-3102, USA. brenner@compbio.berkeley.edu}, author = {Brenner, S. E. }, citeulike-article-id = {447073}, doi = {http://dx.doi.org/10.1038/35093574}, issn = {1471-0056}, journal = {Nat Rev Genet}, keywords = {a\_goodinfo}, month = {October}, number = {10}, pages = {801--809}, posted-at = {2007-11-01 10:10:35}, priority = {2}, title = {A tour of structural genomics.}, url = {http://dx.doi.org/10.1038/35093574}, volume = {2}, year = {2001} }

RIS record

TY - JOUR ID - citeulike:447073 L3 - citeulike-article-id:447073 TI - A tour of structural genomics. JF - Nat Rev Genet VL - 2 IS - 10 SP - 801 EP - 809 AD - Department of Plant and Microbial Biology, University of California, 461A Koshland Hall, Berkeley, California 94720-3102, USA. brenner@compbio.berkeley.edu SN - 1471-0056 N2 - Structural genomics projects aim to provide an experimental or computational three-dimensional model structure for all of the tractable macromolecules that are encoded by complete genomes. To this end, pilot centres worldwide are now exploring the feasibility of large-scale structure determination. Their experimental structures and computational models are expected to yield insight into the molecular function and mechanism of thousands of proteins. The pervasiveness of this information is likely to change the use of structure in molecular biology and biochemistry. KW - a_goodinfo AU - Brenner, SE PY - 2001/10// UR - http://dx.doi.org/10.1038/35093574 ER -

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