Protein structure prediction: inroads to biology.

@article{citeulike:447027, abstract = {In recent years, there has been significant progress in the ability to predict the three-dimensional structure of proteins from their amino acid sequence. Progress has been due to new methods to extract the growing amount of information in sequence and structure databases and improved computational descriptions of protein energetics. This review summarizes recent advances in these areas and describes a number of novel biological applications made possible by structure prediction. Despite remaining challenges, protein structure prediction is becoming an extremely useful tool in understanding phenomena in modern molecular and cell biology.}, address = {Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Center for Computational Biology and Bioinformatics, Columbia University, 1130 St. Nicholas Avenue, Room 815, New York, New York 10032.}, author = {Petrey, D. and Honig, B. }, citeulike-article-id = {447027}, doi = {10.1016/j.molcel.2005.12.005}, issn = {1097-2765}, journal = {Mol Cell}, keywords = {a\_goodinfo}, month = {December}, number = {6}, pages = {811--819}, posted-at = {2007-11-01 10:11:05}, priority = {2}, title = {Protein structure prediction: inroads to biology.}, url = {http://dx.doi.org/10.1016/j.molcel.2005.12.005}, volume = {20}, year = {2005} }

TY - JOUR ID - citeulike:447027 L3 - citeulike-article-id:447027 TI - Protein structure prediction: inroads to biology. JF - Mol Cell VL - 20 IS - 6 SP - 811 EP - 819 AD - Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Center for Computational Biology and Bioinformatics, Columbia University, 1130 St. Nicholas Avenue, Room 815, New York, New York 10032. SN - 1097-2765 N2 - In recent years, there has been significant progress in the ability to predict the three-dimensional structure of proteins from their amino acid sequence. Progress has been due to new methods to extract the growing amount of information in sequence and structure databases and improved computational descriptions of protein energetics. This review summarizes recent advances in these areas and describes a number of novel biological applications made possible by structure prediction. Despite remaining challenges, protein structure prediction is becoming an extremely useful tool in understanding phenomena in modern molecular and cell biology. KW - a_goodinfo AU - Petrey, D AU - Honig, B PY - 2005/12/22/ UR - http://dx.doi.org/10.1016/j.molcel.2005.12.005 ER -