Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology

@article{citeulike:2079857, abstract = {Forty years' experience as a bacterial geneticist has taught me that bacteria possess many cognitive, computational and evolutionary capabilities unimaginable in the first six decades of the twentieth century. Analysis of cellular processes such as metabolism, regulation of protein synthesis, and DNA repair established that bacteria continually monitor their external and internal environments and compute functional outputs based on information provided by their sensory apparatus. Studies of genetic recombination, lysogeny, antibiotic resistance and my own work on transposable elements revealed multiple widespread bacterial systems for mobilizing and engineering DNA molecules. Examination of colony development and organization led me to appreciate how extensive multicellular collaboration is among the majority of bacterial species. Contemporary research in many laboratories on cell-cell signaling, symbiosis and pathogenesis show that bacteria utilise sophisticated mechanisms for intercellular communication and even have the ability to commandeer the basic cell biology of `higher' plants and animals to meet their own needs. This remarkable series of observations requires us to revise basic ideas about biological information processing and recognise that even the smallest cells are sentient beings.}, author = {Shapiro, J. A. }, citeulike-article-id = {2079857}, doi = {http://dx.doi.org/10.1016/j.shpsc.2007.09.010}, journal = {Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences}, keywords = {doctorate, genomics, master, transposon}, month = {December}, number = {4}, pages = {807--819}, posted-at = {2008-05-13 14:45:34}, priority = {2}, title = {Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology}, url = {http://dx.doi.org/10.1016/j.shpsc.2007.09.010}, volume = {38}, year = {2007} }

TY - JOUR ID - citeulike:2079857 L3 - citeulike-article-id:2079857 TI - Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology JF - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences VL - 38 IS - 4 SP - 807 EP - 819 N2 - Forty years' experience as a bacterial geneticist has taught me that bacteria possess many cognitive, computational and evolutionary capabilities unimaginable in the first six decades of the twentieth century. Analysis of cellular processes such as metabolism, regulation of protein synthesis, and DNA repair established that bacteria continually monitor their external and internal environments and compute functional outputs based on information provided by their sensory apparatus. Studies of genetic recombination, lysogeny, antibiotic resistance and my own work on transposable elements revealed multiple widespread bacterial systems for mobilizing and engineering DNA molecules. Examination of colony development and organization led me to appreciate how extensive multicellular collaboration is among the majority of bacterial species. Contemporary research in many laboratories on cell-cell signaling, symbiosis and pathogenesis show that bacteria utilise sophisticated mechanisms for intercellular communication and even have the ability to commandeer the basic cell biology of `higher' plants and animals to meet their own needs. This remarkable series of observations requires us to revise basic ideas about biological information processing and recognise that even the smallest cells are sentient beings. KW - doctorate KW - genomics KW - master KW - transposon AU - Shapiro, JA PY - 2007/12// UR - http://dx.doi.org/10.1016/j.shpsc.2007.09.010 ER -