PARPs Database: A LIMS systems for protein-protein interaction data mining or Laboratory Information management system

@article{citeulike:2149519, abstract = {BACKGROUND:In the apost-genomea era, mass spectrometry (MS) has become an important method for the analysis of proteins and the rapid advancement of this technique, in combination with other proteomics methods, results in an increasing amount of proteome data. This data must be archived and analysed using specialized bioinformatics tools. Description: We herein describe aPARPs database,a a data analysis and management pipeline for liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics. PARPs database is a web-based tool whose features include experiment annotation, protein database searching, protein sequence management, as well as data-mining of the peptides and proteins identified.CONCLUSIONS:Using this pipeline, we have successfully identified several interactions of biological significance between PARP-1 and other proteins, namely RFC-1, 2, 3, 4 and 5.}, author = {Droit, Arnaud and Hunter, Joanna and Rouleau, Michele and Ethier, Chantal and Cloutier, Aude P. and Bourgais, David and Poirier, Guy }, citeulike-article-id = {2149519}, doi = {10.1186/1471-2105-8-483}, journal = {BMC Bioinformatics}, keywords = {database, lims, mass-spec, proteomics}, number = {1}, posted-at = {2007-12-20 03:36:02}, priority = {2}, title = {PARPs Database: A LIMS systems for protein-protein interaction data mining or Laboratory Information management system}, url = {http://dx.doi.org/10.1186/1471-2105-8-483}, volume = {8}, year = {2007} }

TY - JOUR ID - citeulike:2149519 L3 - citeulike-article-id:2149519 TI - PARPs Database: A LIMS systems for protein-protein interaction data mining or Laboratory Information management system JF - BMC Bioinformatics VL - 8 IS - 1 N2 - BACKGROUND:In the apost-genomea era, mass spectrometry (MS) has become an important method for the analysis of proteins and the rapid advancement of this technique, in combination with other proteomics methods, results in an increasing amount of proteome data. This data must be archived and analysed using specialized bioinformatics tools. Description: We herein describe aPARPs database,a a data analysis and management pipeline for liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics. PARPs database is a web-based tool whose features include experiment annotation, protein database searching, protein sequence management, as well as data-mining of the peptides and proteins identified.CONCLUSIONS:Using this pipeline, we have successfully identified several interactions of biological significance between PARP-1 and other proteins, namely RFC-1, 2, 3, 4 and 5. KW - database KW - lims KW - mass-spec KW - proteomics AU - Droit, Arnaud AU - Hunter, Joanna AU - Rouleau, Michele AU - Ethier, Chantal AU - Cloutier, Aude AU - Bourgais, David AU - Poirier, Guy PY - 2007/// UR - http://dx.doi.org/10.1186/1471-2105-8-483 ER -