SMART 5: domains in the context of genomes and networks.

@article{Letunic2006, abstract = {The Simple Modular Architecture Research Tool (SMART) is an online resource (http://smart.embl.de/) used for protein domain identification and the analysis of protein domain architectures. Many new features were implemented to make SMART more accessible to scientists from different fields. The new 'Genomic' mode in SMART makes it easy to analyze domain architectures in completely sequenced genomes. Domain annotation has been updated with a detailed taxonomic breakdown and a prediction of the catalytic activity for 50 SMART domains is now available, based on the presence of essential amino acids. Furthermore, intrinsically disordered protein regions can be identified and displayed. The network context is now displayed in the results page for more than 350 000 proteins, enabling easy analyses of domain interactions.}, author = {Letunic, Ivica and Copley, Richard R. and Pils, Birgit and Pinkert, Stefan and Schultz, J\"{o}rg and Bork, Peer }, citeulike-article-id = {2054443}, doi = {10.1093/nar/gkj079}, journal = {Nucleic Acids Res}, keywords = {alignment, analysis, article-nar, article-pka-pkg, article-predikin, biological, catalysis, catalytic, complex, database, domain, genomics, interface, internet, models, multiprotein, protein, sequence, structure, tertiary, user-computer}, month = {Jan}, number = {Database issue}, pages = {D257--D260}, posted-at = {2007-12-04 03:22:13}, priority = {2}, title = {SMART 5: domains in the context of genomes and networks.}, url = {10.1093/nar/gkj079}, volume = {34}, year = {2006} }

TY - JOUR ID - Letunic2006 L3 - citeulike-article-id:2054443 TI - SMART 5: domains in the context of genomes and networks. JF - Nucleic Acids Res VL - 34 IS - Database issue SP - D257 EP - D260 N2 - The Simple Modular Architecture Research Tool (SMART) is an online resource (http://smart.embl.de/) used for protein domain identification and the analysis of protein domain architectures. Many new features were implemented to make SMART more accessible to scientists from different fields. The new 'Genomic' mode in SMART makes it easy to analyze domain architectures in completely sequenced genomes. Domain annotation has been updated with a detailed taxonomic breakdown and a prediction of the catalytic activity for 50 SMART domains is now available, based on the presence of essential amino acids. Furthermore, intrinsically disordered protein regions can be identified and displayed. The network context is now displayed in the results page for more than 350 000 proteins, enabling easy analyses of domain interactions. KW - alignment KW - analysis KW - article-nar KW - article-pka-pkg KW - article-predikin KW - biological KW - catalysis KW - catalytic KW - complex KW - database KW - domain KW - genomics KW - interface KW - internet KW - models KW - multiprotein KW - protein KW - sequence KW - structure KW - tertiary KW - user-computer AU - Letunic, Ivica AU - Copley, Richard AU - Pils, Birgit AU - Pinkert, Stefan AU - Schultz, Jörg AU - Bork, Peer PY - 2006/Jan// UR - http://dx.doi.org/10.1093/nar/gkj079 ER -