Intracellular targeting of protein kinases and phosphatases.

@article{citeulike:2042312, abstract = {Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger-mediated signaling events. Localization of the cAMP-dependent protein kinase (PKA) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). This study focused on recent advances that further our understanding of AKAPs, with particular emphasis on the bidirectional regulation of signaling events by AKAP signaling complexes and their contribution to the control of actin reorganization events.}, address = {Howard Hughes Medical Institute, Vollum Institute, Portland, Oregon 97201-3098, USA.}, author = {Alto, N. and Carlisle Michel, J. J. and Dodge, K. L. and Langeberg, L. K. and Scott, J. D. }, citeulike-article-id = {2042312}, issn = {0012-1797}, journal = {Diabetes}, keywords = {akap, camp, kinase, recruitment, signaling, substrate}, month = {December}, posted-at = {2007-12-02 07:09:46}, priority = {2}, title = {Intracellular targeting of protein kinases and phosphatases.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12475780}, volume = {51 Suppl 3}, year = {2002} }

TY - JOUR ID - citeulike:2042312 L3 - citeulike-article-id:2042312 TI - Intracellular targeting of protein kinases and phosphatases. JF - Diabetes VL - 51 Suppl 3 AD - Howard Hughes Medical Institute, Vollum Institute, Portland, Oregon 97201-3098, USA. SN - 0012-1797 N2 - Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger-mediated signaling events. Localization of the cAMP-dependent protein kinase (PKA) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). This study focused on recent advances that further our understanding of AKAPs, with particular emphasis on the bidirectional regulation of signaling events by AKAP signaling complexes and their contribution to the control of actin reorganization events. KW - akap KW - camp KW - kinase KW - recruitment KW - signaling KW - substrate AU - Alto, N AU - Carlisle Michel, JJ AU - Dodge, KL AU - Langeberg, LK AU - Scott, JD PY - 2002/12// UR - http://view.ncbi.nlm.nih.gov/pubmed/12475780 ER -