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mtagaya sirna [48 articles]

最近 mtagaya さんのライブラリに追加された論文の中から タグ sirna. You can also see everyone's sirna.
  • Small interfering RNA-induced transcriptional gene silencing in human cells.
    Science (New York, N.Y.), Vol. 305, No. 5688. (27 August 2004), pp. 1289-1292.
    by KV Morris, SW Chan, SE Jacobsen, DJ Looney
    posted to rnai sirna by mtagaya on 2008-08-16 01:33:16 as **
  • Analysis of siRNA specificity on targets with double-nucleotide mismatches.
    Nucleic acids research (17 April 2008)
    by Cecilia Dahlgren, Hong-Yan Y Zhang, Quan Du, Maria Grahn, Gunnar Norstedt, Claes Wahlestedt, Zicai Liang
    posted to off-target sirna by mtagaya on 2008-05-22 10:07:15 as ** along with 1 person jyuh
  • Gene expression silencing with specific small interfering RNA goes beyond specificity a study of key parameters to take into account in the onset of small interfering RNA off-target effects
    FEBS Journal, Vol. 275, No. 11. (June 2008), pp. 2738-2753.
    posted to off-target sirna by mtagaya on 2008-05-22 10:07:01 as ** along with 1 person jyuh
  • Experimental validation of the importance of seed complement frequency to siRNA specificity.
    RNA (New York, N.Y.), Vol. 14, No. 5. (May 2008), pp. 853-861.
    posted to off-target sirna by mtagaya on 2008-04-24 03:53:17 as **
  • Hidden layers of human small RNAs
    BMC Genomics, Vol. 9, No. 1. (2008)
    by Hideya Kawaji, Mari Nakamura, Yukari Takahashi, Albin Sandelin, Shintaro Katayama, Shiro Fukuda, Carsten Daub, Chikatoshi Kai, Jun Kawai, Jun Yasuda, Piero Carninci, Yoshihide Hayashizaki
    posted to microrna rna sirna by mtagaya on 2008-04-23 04:27:28 as ** along with 3 people heliopais maralena bertelsen
  • Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
    Nucleic Acids Res (11 February 2008)
    by Kumiko Ui-Tei, Yuki Naito, Shuhei Zenno, Kenji Nishi, Kenji Yamato, Fumitaka Takahashi, Aya Juni, Kaoru Saigo
  • siRNA-mediated off-target gene silencing triggered by a 7 nt complementation
    Nucleic Acids Research, Vol. 33, No. 14. (2005), pp. 4527-4535.
    by Xiaoyu Lin, Xiaoan Ruan, Mark G Anderson, Jeffrey A Mcdowell, Paul E Kroeger, Stephen W Fesik, Yu Shen
    posted to off-target sirna by mtagaya on 2008-04-15 15:53:59 as **
  • A computational study of off-target effects of RNA interference
    Nucleic Acids Research, Vol. 33, No. 6. (2005), pp. 1834-1847.
    by Shibin Qiu, Coen M Adema, Terran Lane
  • A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
    Nucleic Acids Research, Vol. 33, No. 5. (2005), pp. 1671-1677.
    by Quan Du, Hakan Thonberg, Jue Wang, Claes Wahlestedt, Zicai Liang
    posted to off-target sirna by mtagaya on 2008-04-15 15:44:15 as ** along with 1 person tardigrade
  • A systematic analysis of the effect of target RNA structure on RNA interference.
    Nucleic acids research, Vol. 35, No. 13. (2007), pp. 4322-4330.
    posted to sirna target by mtagaya on 2008-04-03 02:51:47 as ** along with 1 person puranjoy_b
  • Effect of target secondary structure on RNAi efficiency
    RNA (7 August 2007), rna.546207.
    by Yu Shao, Chi Y Chan, Anil Maliyekkel, Charles E Lawrence, Igor B Roninson, Ye Ding
    posted to sirna target by mtagaya on 2008-04-03 02:51:10 as ** along with 4 people puranjoy_b Hosna ilh fengqian
  • Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study.
    Biotechnology and bioengineering (1 February 2008)
    by Joseph A A Gredell, Angela K K Berger, S Patrick P Walton
    posted to sirna target by mtagaya on 2008-04-03 02:50:44 as ** along with 1 person puranjoy_b
  • siRNA target site secondary structure predictions using local stable substructures.
    Nucleic Acids Res, Vol. 33, No. 3. (2005)
    by BS Heale, HS Soifer, C Bowers, JJ Rossi
    posted to sirna structure target by mtagaya on 2008-02-26 08:47:43 as ** along with 1 person tardigrade
  • Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions.
    J Mol Biol, Vol. 348, No. 4. (13 May 2005), pp. 883-893.
    posted to bioinformatics prediction sirna target by mtagaya on 2008-02-25 01:44:39 as **
  • Efficient siRNA selection using hybridization thermodynamics.
    Nucleic Acids Res, Vol. 36, No. 2. (February 2008), pp. 640-647.
    by ZJ Lu, DH Mathews
    posted to bioinformatics sirna by mtagaya on 2008-02-05 06:03:15 as ** along with 2 people puranjoy_b jyuh
  • A probability-based approach for the analysis of large-scale RNAi screens
    Nature Methods, Vol. 4, No. 10. (09 September 2007), pp. 847-849.
    by Renate König, Chih-Yuan Chiang, Buu P Tu, Frank S Yan, Paul D Dejesus, Angelica Romero, Tobias Bergauer, Anthony Orth, Ute Krueger, Yingyao Zhou, Sumit K Chanda
    posted to off-target sirna by mtagaya on 2008-01-22 02:57:59 as ** along with 1 person jyuh
  • Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity.
    Adv Drug Deliv Rev, Vol. 59, No. 2-3. (30 March 2007), pp. 164-182.
    by S Akhtar, I Benter
    posted to rnai sirna by mtagaya on 2008-01-07 08:27:32 as ** along with 1 person jyuh
  • Structural Basis for Double-Stranded RNA Processing by Dicer
    Science, Vol. 311, No. 5758. (13 January 2006), pp. 195-198.
    by Ian J Macrae, Kaihong Zhou, Fei Li, Adrian Repic, Angela N Brooks, Zacheus W Cande, Paul D Adams, Jennifer A Doudna
  • Comparison of approaches for rational siRNA design leading to a new efficient and transparent method.
    Nucleic Acids Res (10 April 2007)
    by Olga Matveeva, Yury Nechipurenko, Leo Rossi, Barry Moore, Pål Sætrom, Aleksey Y Y Ogurtsov, John F F Atkins, Svetlana A A Shabalina
    posted to bioinformatics sirna by mtagaya on 2007-10-30 06:24:15 as ** along with 2 people jyuh tardigrade
  • Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities
    Nucl. Acids Res., Vol. 35, No. 18. (25 September 2007), e123.
    by Masatoshi Ichihara, Yoshiki Murakumo, Akio Masuda, Toru Matsuura, Naoya Asai, Mayumi Jijiwa, Maki Ishida, Jun Shinmi, Hiroshi Yatsuya, Shanlou Qiao, Masahide Takahashi, Kinji Ohno
    posted to sirna by mtagaya on 2007-10-26 01:17:31 as **
  • Distance constraints between microRNA target sites dictate efficacy and cooperativity.
    Nucleic Acids Res (27 March 2007)
    by Pål Sætrom, Bret S E S Heale, Ola Snøve, Lars Aagaard, Jessica Alluin, John J J Rossi
  • More complete gene silencing by fewer siRNAs: transparent optimized design and biophysical signature
    Nucl. Acids Res., Vol. 35, No. 2. (28 January 2007), pp. 433-440.
    by Istvan Ladunga
    posted to bioinformatics sirna by mtagaya on 2007-09-21 01:57:28 as ** along with 2 people puranjoy_b cthachuk
  • Novel insights into RNAi off-target effects using C. elegans paralogs
    BMC Genomics, Vol. 8 (19 April 2007), 106.
    by Jean-Francois Rual, Niels Klitgord, Guillaume Achaz
  • Combinatorial RNAi for quantitative protein network analysis.
    Proc Natl Acad Sci U S A, Vol. 104, No. 16. (17 April 2007), pp. 6579-6584.
    posted to bioinformatics sirna by mtagaya on 2007-09-21 01:56:03 as ** along with 1 person jyuh
  • Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
    BMC Bioinformatics, Vol. 8 (22 May 2007), 164.
    by Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shyen E Chen, Jiun-Ching Chen, Ming-Te Yang, Pan-Chyr Yang, Pei-Chun Chang, Jeremy JW Chen
    posted to bioinformatics sirna by mtagaya on 2007-09-21 01:55:03 as **
  • Specific residues at every third position of siRNA shape its efficient RNAi activity.
    Nucleic Acids Res (26 January 2007)
    by Takayuki Katoh, Tsutomu Suzuki
  • MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms.
    Proc Natl Acad Sci U S A, Vol. 100, No. 17. (19 August 2003), pp. 9779-9784.
    by Y Zeng, R Yi, BR Cullen
    posted to mirna off-target sirna by mtagaya on 2007-05-10 09:54:33 as **
  • Expression profiling reveals off-target gene regulation by RNAi.
    Nat Biotechnol, Vol. 21, No. 6. (June 2003), pp. 635-637.
    by AL Jackson, SR Bartz, J Schelter, SV Kobayashi, J Burchard, M Mao, B Li, G Cavet, PS Linsley
    posted to bioinformatics off-target sirna by mtagaya on 2007-05-10 09:46:36 as ** along with 1 person Hosna
  • Design of a genome-wide siRNA library using an artificial neural network
    Nature Biotechnology, Vol. 23, No. 8. (17 July 2005), pp. 995-1001.
    by Dieter Huesken, Joerg Lange, Craig Mickanin, Jan Weiler, Fred Asselbergs, Justin Warner, Brian Meloon, Sharon Engel, Avi Rosenberg, Dalia Cohen, Mark Labow, Mischa Reinhardt, François Natt, Jonathan Hall
    posted to bioinformatics sirna by mtagaya on 2007-05-10 09:43:37 as ** along with 1 person tardigrade
  • Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency
    Nature Biotechnology, Vol. 23, No. 11. (30 October 2005), pp. 1440-1444.
    by Volker Patzel, Sascha Rutz, Isabell Dietrich, Christian Köberle, Alexander Scheffold, Stefan HE Kaufmann
  • Efficient prediction of siRNAs with siRNArules 1.0: An open-source JAVA approach to siRNA algorithms.
    RNA (26 July 2006)
    by Torgeir Holen
    posted to bioinformatics sirna by mtagaya on 2007-05-10 09:38:50 as ** along with 2 people tardigrade mgantier
  • Rational siRNA design for RNA interference.
    Nat Biotechnol, Vol. 22, No. 3. (March 2004), pp. 326-330.
    posted to bioinformatics sirna by mtagaya on 2007-05-10 09:37:19 as ** along with 1 person zebkhan
  • In silico selection of active siRNA.
    Drug Discov Today, Vol. 12, No. 3-4. (February 2007), pp. 139-148.
    by V Patzel
    posted to sirna by mtagaya on 2007-04-24 09:23:51 as read along with 4 people puranjoy_b jyuh tardigrade bsmagic
  • RNA interference using boranophosphate siRNAs: structure-activity relationships.
    Nucleic Acids Res, Vol. 32, No. 20. (2004), pp. 5991-6000.
    posted to boranophosphate sirna by mtagaya on 2007-04-05 04:14:46 as **
  • High potency silencing by single-stranded boranophosphate siRNA.
    Nucleic Acids Res, Vol. 34, No. 9. (2006), pp. 2773-2781.
    by AH Hall, J Wan, A Spesock, Z Sergueeva, BR Shaw, KA Alexander
    posted to boranophosphate sirna by mtagaya on 2007-04-05 04:14:18 as **
  • A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis.
    Genes Dev, Vol. 19, No. 18. (15 September 2005), pp. 2164-2175.
    by M Yoshikawa, A Peragine, MY Park, RS Poethig
    posted to plant sirna by mtagaya on 2006-11-17 09:18:23 as **
  • Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs.
    Mol Cell, Vol. 16, No. 1. (8 October 2004), pp. 69-79.
    posted to plant sirna by mtagaya on 2006-11-17 09:17:17 as **
  • SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis.
    Genes Dev, Vol. 18, No. 19. (1 October 2004), pp. 2368-2379.
    by A Peragine, M Yoshikawa, G Wu, HL Albrecht, RS Poethig
    posted to plant sirna by mtagaya on 2006-11-17 09:15:40 as **
  • A Two-Hit Trigger for siRNA Biogenesis in Plants.
    Cell, Vol. 127, No. 3. (3 November 2006), pp. 565-577.
    by MJ Axtell, C Jan, R Rajagopalan, DP Bartel
  • siRNAs and DNA Methylation Do a Two-Step to Silence Tandem Sequences
    PLoS Biology, Vol. 4, No. 11. (1 November 2006)
    by Richard Robinson
    posted to methylation repeat sirna by mtagaya on 2006-11-17 01:18:10 as **
  • Two-Step Recruitment of RNA-Directed DNA Methylation to Tandem Repeats.
    PLoS Biol, Vol. 4, No. 11. (24 October 2006)
    by Simon W-L W Chan, Xiaoyu Zhang, Yana V V Bernatavichute, Steven E E Jacobsen
    posted to methylation repeat sirna by mtagaya on 2006-11-17 01:17:03 as ** along with 1 person braingrind
  • Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation
    Nature (24 September 2006)
    by Yijun Qi, Xingyue He, Xiu-Jie Wang, Oleksiy Kohany, Jerzy Jurka, Gregory J Hannon
  • Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells.
    Nat Struct Mol Biol (27 August 2006)
    by Daniel H H Kim, Louisa M M Villeneuve, Kevin V V Morris, John J J Rossi
  • Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes.
    RNA (14 June 2006)
    by Xiang Liu, Feng Jiang, Savitha Kalidas, Dean Smith, Qinghua Liu
    posted to dicer risc rnai sirna by mtagaya on 2006-08-18 02:53:12 as ** along with 1 person tardigrade
  • Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras
    Nature Biotechnology, Vol. 24, No. 8. (25 June 2006), pp. 1005-1015.
    by James O Mcnamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A Sullenger, Paloma H Giangrande
    posted to delivery rnai sirna by mtagaya on 2006-08-18 02:52:04 as ** along with 3 people jyuh tardigrade mgantier
  • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells.
    J Biol Chem, Vol. 278, No. 45. (7 November 2003), pp. 44312-44319.
    by S Saxena, ZO Jónsson, A Dutta
    posted to off-target rnai sirna by mtagaya on 2006-07-11 10:23:31 as ** along with 1 person chenlc03
  • Mismatched siRNAs downregulate mRNAs as a function of target site location.
    FEBS Lett (5 June 2006)
    by Scott E E Martin, Natasha J J Caplen
  • Artificial control of gene expression in mammalian cells by modulating RNA interference through aptamer-small molecule interaction.
    RNA, Vol. 12, No. 5. (May 2006), pp. 710-716.
    by CI An, VB Trinh, Y Yokobayashi
    posted to rnai sirna by mtagaya on 2006-06-09 02:28:00 as ** along with 1 person jyuh
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