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mtagaya off-target [28 articles]

最近 mtagaya さんのライブラリに追加された論文の中から タグ off-target. You can also see everyone's off-target.
  • Analysis of siRNA specificity on targets with double-nucleotide mismatches.
    Nucleic acids research (17 April 2008)
    by Cecilia Dahlgren, Hong-Yan Y Zhang, Quan Du, Maria Grahn, Gunnar Norstedt, Claes Wahlestedt, Zicai Liang
    posted to sirna off-target by mtagaya on 2008-05-22 10:07:15 as ** along with 1 person jyuh
  • Gene expression silencing with specific small interfering RNA goes beyond specificity a study of key parameters to take into account in the onset of small interfering RNA off-target effects
    FEBS Journal, Vol. 275, No. 11. (June 2008), pp. 2738-2753.
    by Vankoningsloo, Sebastien, De Longueville, Francoise, Evrard, Stephanie, Rahier, Pierre, Houbion, Andree, Fattaccioli, Antoine, Gastellier, Melanie, Remacle, Jose, Raes, Martine, Renard, Patricia, Arnould, Thierry
    posted to sirna off-target by mtagaya on 2008-05-22 10:07:01 as ** along with 1 person jyuh
  • Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing.
    RNA (8 May 2006)
    by Aimee L L Jackson, Julja Burchard, Devin Leake, Angela Reynolds, Janell Schelter, Jie Guo, Jason M M Johnson, Lee Lim, Jon Karpilow, Kim Nichols, William Marshall, Anastasia Khvorova, Peter S S Linsley
    posted to rnai off-target by mtagaya on 2008-05-01 09:05:08 as ** along with 2 people tardigrade lhonigberg
  • Experimental validation of the importance of seed complement frequency to siRNA specificity.
    RNA (New York, N.Y.), Vol. 14, No. 5. (May 2008), pp. 853-861.
    by EM Anderson, A Birmingham, S Baskerville, A Reynolds, E Maksimova, D Leake, Y Fedorov, J Karpilow, A Khvorova
    posted to sirna off-target by mtagaya on 2008-04-24 03:53:17 as **
  • Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
    Nucleic Acids Res (11 February 2008)
    by Kumiko Ui-Tei, Yuki Naito, Shuhei Zenno, Kenji Nishi, Kenji Yamato, Fumitaka Takahashi, Aya Juni, Kaoru Saigo
    posted to off-target sirna by mtagaya on 2008-04-17 15:13:21 as ** along with 3 people and 1 group jyuh sebastien_vigneau wsjames Oxford Virology
  • siRNA-mediated off-target gene silencing triggered by a 7 nt complementation
    Nucleic Acids Research, Vol. 33, No. 14. (2005), pp. 4527-4535.
    by Xiaoyu Lin, Xiaoan Ruan, Mark G Anderson, Jeffrey A Mcdowell, Paul E Kroeger, Stephen W Fesik, Yu Shen
    posted to off-target sirna by mtagaya on 2008-04-15 15:53:59 as **
  • A computational study of off-target effects of RNA interference
    Nucleic Acids Research, Vol. 33, No. 6. (2005), pp. 1834-1847.
    by Shibin Qiu, Coen M Adema, Terran Lane
    posted to off-target sirna by mtagaya on 2008-04-15 15:51:28 as ** along with 1 person jiny
  • A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
    Nucleic Acids Research, Vol. 33, No. 5. (2005), pp. 1671-1677.
    by Quan Du, Hakan Thonberg, Jue Wang, Claes Wahlestedt, Zicai Liang
    posted to off-target sirna by mtagaya on 2008-04-15 15:44:15 as ** along with 1 person tardigrade
  • Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect.
    Nucleic Acids Res (20 December 2007)
    by Paul R R Clark, Jordan S S Pober, Martin S S Kluger
    posted to off-target rnai by mtagaya on 2008-02-29 05:43:56 as ** along with 1 person YamaPing
  • A probability-based approach for the analysis of large-scale RNAi screens
    Nature Methods, Vol. 4, No. 10. (09 September 2007), pp. 847-849.
    by Renate König, Chih-Yuan Chiang, Buu P Tu, Frank S Yan, Paul D Dejesus, Angelica Romero, Tobias Bergauer, Anthony Orth, Ute Krueger, Yingyao Zhou, Sumit K Chanda
    posted to off-target sirna by mtagaya on 2008-01-22 02:57:59 as ** along with 1 person jyuh
  • Advances in MicroRNAs: Implications for Gene Therapists.
    Hum Gene Ther (19 December 2007)
    by Rebecca T T Marquez, Anton P P McCaffrey
    posted to microrna off-target rnai by mtagaya on 2008-01-07 08:24:52 as ** along with 1 person dchughes
  • An RNA targeted to the HIV-1 LTR promoter modulates indiscriminate off-target gene activation
    Nucl. Acids Res. (24 October 2007), gkm847.
    by Marc S Weinberg, Samantha Barichievy, Lana Schaffer, Jiang Han, Kevin V Morris
    posted to hiv off-target rna by mtagaya on 2007-10-26 01:34:56 as **
  • Distance constraints between microRNA target sites dictate efficacy and cooperativity.
    Nucleic Acids Res (27 March 2007)
    by Pål Sætrom, Bret S E S Heale, Ola Snøve, Lars Aagaard, Jessica Alluin, John J J Rossi
    posted to microrna off-target sirna by mtagaya on 2007-10-25 07:46:19 as ** along with 2 people and 1 group tardigrade andersbj microRNA
  • Novel insights into RNAi off-target effects using C. elegans paralogs
    BMC Genomics, Vol. 8 (19 April 2007), 106.
    by Jean-Francois Rual, Niels Klitgord, Guillaume Achaz
    posted to bioinformatics off-target sirna by mtagaya on 2007-09-21 01:56:29 as ** along with 1 person jyuh
  • MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms.
    Proc Natl Acad Sci U S A, Vol. 100, No. 17. (19 August 2003), pp. 9779-9784.
    by Y Zeng, R Yi, BR Cullen
    posted to mirna off-target sirna by mtagaya on 2007-05-10 09:54:33 as **
  • A microRNA in a multiple-turnover RNAi enzyme complex.
    Science, Vol. 297, No. 5589. (20 September 2002), pp. 2056-2060.
    by G Hutvágner, PD Zamore
    posted to mirna off-target rnai by mtagaya on 2007-05-10 09:53:09 as ** along with 1 person ecattell
  • Expression profiling reveals off-target gene regulation by RNAi.
    Nat Biotechnol, Vol. 21, No. 6. (June 2003), pp. 635-637.
    by AL Jackson, SR Bartz, J Schelter, SV Kobayashi, J Burchard, M Mao, B Li, G Cavet, PS Linsley
    posted to bioinformatics off-target sirna by mtagaya on 2007-05-10 09:46:36 as ** along with 1 person Hosna
  • siRNAs can function as miRNAs.
    Genes Dev, Vol. 17, No. 4. (15 February 2003), pp. 438-442.
    by JG Doench, CP Petersen, PA Sharp
    posted to microrna ncrna off-target rnai by mtagaya on 2006-10-16 06:04:28 as ** along with 2 people evaf tardigrade
  • Prevalence of off-target effects in Drosophila RNA interference screens
    Nature (10 September 2006)
    by Yong Ma, Adrian Creanga, Lawrence Lum, Philip A Beachy
    posted to off-target rnai by mtagaya on 2006-09-25 08:15:33 as ** along with 1 person lhonigberg
  • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells.
    J Biol Chem, Vol. 278, No. 45. (7 November 2003), pp. 44312-44319.
    by S Saxena, ZO Jónsson, A Dutta
    posted to off-target rnai sirna by mtagaya on 2006-07-11 10:23:31 as ** along with 1 person chenlc03
  • Mismatched siRNAs downregulate mRNAs as a function of target site location.
    FEBS Lett (5 June 2006)
    by Scott E E Martin, Natasha J J Caplen
    posted to microrna ncrna off-target rnai sirna by mtagaya on 2006-07-11 06:09:05 as read along with 2 people and 1 group tardigrade andersbj microRNA
  • A computational study of off-target effects of RNA interference.
    Nucleic Acids Res, Vol. 33, No. 6. (2005), pp. 1834-1847.
    by S Qiu, CM Adema, T Lane
    posted to bioinformatics off-target rnai by mtagaya on 2006-05-11 07:44:45 as **
  • notes Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity.
    RNA (8 May 2006)
    by Aimee L L Jackson, Julja Burchard, Janell Schelter, B Nelson N Chau, Michele Cleary, Lee Lim, Peter S S Linsley
    posted to off-target rnai by mtagaya on 2006-05-11 07:29:29 as read along with 3 people ttjoseph tardigrade lhonigberg
  • Off-target effects by siRNA can induce toxic phenotype.
    RNA (8 May 2006)
    by Yuriy Fedorov, Emily M M Anderson, Amanda Birmingham, Angela Reynolds, Jon Karpilow, Kathryn Robinson, Devin Leake, William S S Marshall, Anastasia Khvorova
    posted to off-target rnai by mtagaya on 2006-05-11 07:28:27 as ** along with 2 people tardigrade lhonigberg
  • Many commonly used siRNAs risk off-target activity.
    Biochem Biophys Res Commun, Vol. 319, No. 1. (18 June 2004), pp. 256-263.
    by O Snøve, T Holen
    posted to bioinformatics off-target rnai by mtagaya on 2006-05-11 07:23:23 as **
  • Accelerated off-target search algorithm for siRNA.
    Bioinformatics, Vol. 21, No. 8. (15 April 2005), pp. 1316-1324.
    by T Yamada, S Morishita
    posted to bioinformatics off-target rnai by mtagaya on 2006-05-11 07:22:39 as **
  • siRNA-mediated off-target gene silencing triggered by a 7 nt complementation.
    Nucleic Acids Res, Vol. 33, No. 14. (2005), pp. 4527-4535.
    by X Lin, X Ruan, MG Anderson, JA McDowell, PE Kroeger, SW Fesik, Y Shen
    posted to off-target rnai by mtagaya on 2006-04-19 09:25:49 as **
  • 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
    Nature Methods, Vol. 3, No. 3. (17 February 2006), pp. 199-204.
    by Amanda Birmingham, Emily M Anderson, Angela Reynolds, Diane Ilsley-Tyree, Devin Leake, Yuriy Fedorov, Scott Baskerville, Elena Maksimova, Kathryn Robinson, Jon Karpilow, William S Marshall, Anastasia Khvorova
    posted to off-target rnai by mtagaya on 2006-04-19 09:24:53 as **
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