Correlated neuronal discharge rate and its implications for psychophysical performance.

@article{citeulike:87657, abstract = {Single neurons can signal subtle changes in the sensory environment with surprising fidelity, often matching the perceptual sensitivity of trained psychophysical observers. This similarity poses an intriguing puzzle: why is psychophysical sensitivity not greater than that of single neurons? Pooling responses across neurons should average out noise in the activity of single cells, leading to substantially improved psychophysical performance. If, however, noise is correlated among these neurons, the beneficial effects of pooling would be diminished. To assess correlation within a pool, the responses of pairs of neurons were recorded simultaneously during repeated stimulus presentations. We report here that the observed covariation in spike count was relatively weak, the correlation coefficient averaging 0.12. A theoretical analysis revealed, however, that weak correlation can limit substantially the signalling capacity of the pool. In addition, theory suggests a relationship between neuronal responses and psychophysical decisions which may prove useful for identifying cell populations underlying specific perceptual capacities.}, address = {Department of Neurobiology, Stanford University School of Medicine, California 94305.}, author = {Zohary, E. and Shadlen, M. N. and Newsome, W. T. }, citeulike-article-id = {87657}, doi = {http://dx.doi.org/10.1038/370140a0}, issn = {0028-0836}, journal = {Nature}, keywords = {quals}, month = {July}, number = {6485}, pages = {140--143}, posted-at = {2007-06-04 16:39:07}, priority = {0}, title = {Correlated neuronal discharge rate and its implications for psychophysical performance.}, url = {http://dx.doi.org/10.1038/370140a0}, volume = {370}, year = {1994} }

TY - JOUR ID - citeulike:87657 L3 - citeulike-article-id:87657 TI - Correlated neuronal discharge rate and its implications for psychophysical performance. JF - Nature VL - 370 IS - 6485 SP - 140 EP - 143 AD - Department of Neurobiology, Stanford University School of Medicine, California 94305. SN - 0028-0836 N2 - Single neurons can signal subtle changes in the sensory environment with surprising fidelity, often matching the perceptual sensitivity of trained psychophysical observers. This similarity poses an intriguing puzzle: why is psychophysical sensitivity not greater than that of single neurons? Pooling responses across neurons should average out noise in the activity of single cells, leading to substantially improved psychophysical performance. If, however, noise is correlated among these neurons, the beneficial effects of pooling would be diminished. To assess correlation within a pool, the responses of pairs of neurons were recorded simultaneously during repeated stimulus presentations. We report here that the observed covariation in spike count was relatively weak, the correlation coefficient averaging 0.12. A theoretical analysis revealed, however, that weak correlation can limit substantially the signalling capacity of the pool. In addition, theory suggests a relationship between neuronal responses and psychophysical decisions which may prove useful for identifying cell populations underlying specific perceptual capacities. KW - quals AU - Zohary, E AU - Shadlen, MN AU - Newsome, WT PY - 1994/07/14/ UR - http://dx.doi.org/10.1038/370140a0 ER -