RNA granules.

by: P Anderson, N Kedersha

J Cell Biol, Vol. 172, No. 6. (13 March 2006), pp. 803-808.

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Abstract

Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress granules and processing bodies), and neurons (neuronal granules) have emerged as important players in the posttranscriptional regulation of gene expression. RNA granules contain various ribosomal subunits, translation factors, decay enzymes, helicases, scaffold proteins, and RNA-binding proteins, and they control the localization, stability, and translation of their RNA cargo. We review the relationship between different classes of these granules and discuss how spatial organization regulates messenger RNA translation/decay.

@article{citeulike:1229574, abstract = {Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress granules and processing bodies), and neurons (neuronal granules) have emerged as important players in the posttranscriptional regulation of gene expression. RNA granules contain various ribosomal subunits, translation factors, decay enzymes, helicases, scaffold proteins, and RNA-binding proteins, and they control the localization, stability, and translation of their RNA cargo. We review the relationship between different classes of these granules and discuss how spatial organization regulates messenger RNA translation/decay.}, address = {Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA 02115, USA.}, author = {Anderson, P. and Kedersha, N. }, citeulike-article-id = {1229574}, doi = {10.1083/jcb.200512082}, issn = {0021-9525}, journal = {J Cell Biol}, keywords = {granules, rna}, month = {March}, number = {6}, pages = {803--808}, posted-at = {2007-04-16 11:32:18}, priority = {0}, title = {RNA granules.}, url = {http://dx.doi.org/10.1083/jcb.200512082}, volume = {172}, year = {2006} }

RIS record

TY - JOUR ID - citeulike:1229574 L3 - citeulike-article-id:1229574 TI - RNA granules. JF - J Cell Biol VL - 172 IS - 6 SP - 803 EP - 808 AD - Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA 02115, USA. SN - 0021-9525 N2 - Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress granules and processing bodies), and neurons (neuronal granules) have emerged as important players in the posttranscriptional regulation of gene expression. RNA granules contain various ribosomal subunits, translation factors, decay enzymes, helicases, scaffold proteins, and RNA-binding proteins, and they control the localization, stability, and translation of their RNA cargo. We review the relationship between different classes of these granules and discuss how spatial organization regulates messenger RNA translation/decay. KW - granules KW - rna AU - Anderson, P AU - Kedersha, N PY - 2006/03/13/ UR - http://dx.doi.org/10.1083/jcb.200512082 ER -

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