Endosomal trafficking of AMPA-type glutamate receptors

@article{citeulike:2681007, abstract = {Many different forms of synaptic plasticity have been shown to ultimately modulate the number of AMPA-type glutamate receptors at the synapse. This trafficking involves lateral movements between synaptic and extrasynaptic sites at the neuron surface, as well as vesicular transport between the plasma membrane and intracellular compartments. Several new studies have shed light on the location and regulation of AMPA-type receptor (AMPAR) endocytosis, their intracellular sorting to divergent pathways at the level of endosomes, and the mechanism and sites of receptor recycling. This review summarizes this recent data on the trafficking along the endocytic pathway, and follows the path of internalized AMPAR from endocytosis up to sites of recycling.}, author = {Hirling, H. }, citeulike-article-id = {2681007}, doi = {10.1016/j.neuroscience.2008.02.057}, journal = {Neuroscience}, keywords = {ampar, dendritic\_spines, endocytosis, neurons, review}, posted-at = {2008-04-17 09:13:30}, priority = {0}, title = {Endosomal trafficking of AMPA-type glutamate receptors}, url = {http://dx.doi.org/10.1016/j.neuroscience.2008.02.057}, volume = {In Press, Corrected Proof} }

TY - JOUR ID - citeulike:2681007 L3 - citeulike-article-id:2681007 TI - Endosomal trafficking of AMPA-type glutamate receptors JF - Neuroscience VL - In Press, Corrected Proof N2 - Many different forms of synaptic plasticity have been shown to ultimately modulate the number of AMPA-type glutamate receptors at the synapse. This trafficking involves lateral movements between synaptic and extrasynaptic sites at the neuron surface, as well as vesicular transport between the plasma membrane and intracellular compartments. Several new studies have shed light on the location and regulation of AMPA-type receptor (AMPAR) endocytosis, their intracellular sorting to divergent pathways at the level of endosomes, and the mechanism and sites of receptor recycling. This review summarizes this recent data on the trafficking along the endocytic pathway, and follows the path of internalized AMPAR from endocytosis up to sites of recycling. KW - ampar KW - dendritic_spines KW - endocytosis KW - neurons KW - review AU - Hirling, H UR - http://dx.doi.org/10.1016/j.neuroscience.2008.02.057 ER -