Integrating molecular and network biology to decode endocytosis

@article{citeulike:1586076, abstract = {The strength of network biology lies in its ability to derive cell biological information without a priori mechanistic or molecular knowledge. It is shown here how a careful understanding of a given biological pathway can refine an interactome approach. This permits the elucidation of additional design principles and of spatio-temporal dynamics behind pathways, and aids in experimental design and interpretation.}, author = {Schmid, Eva M. and Mcmahon, Harvey T. }, citeulike-article-id = {1586076}, doi = {10.1038/nature06031}, journal = {Nature}, keywords = {clathrin, endocytosis, model}, number = {7156}, pages = {883--888}, posted-at = {2008-04-01 11:08:50}, priority = {0}, title = {Integrating molecular and network biology to decode endocytosis}, url = {http://dx.doi.org/10.1038/nature06031}, volume = {448}, year = {2007} }

TY - JOUR ID - citeulike:1586076 L3 - citeulike-article-id:1586076 TI - Integrating molecular and network biology to decode endocytosis JF - Nature VL - 448 IS - 7156 SP - 883 EP - 888 N2 - The strength of network biology lies in its ability to derive cell biological information without a priori mechanistic or molecular knowledge. It is shown here how a careful understanding of a given biological pathway can refine an interactome approach. This permits the elucidation of additional design principles and of spatio-temporal dynamics behind pathways, and aids in experimental design and interpretation. KW - clathrin KW - endocytosis KW - model AU - Schmid, Eva AU - Mcmahon, Harvey PY - 2007//23/ UR - http://dx.doi.org/10.1038/nature06031 ER -