Mechanisms of Top-Down Facilitation in Perception of Visual Objects Studied by fMRI.

@article{citeulike:954374, abstract = {Prior knowledge regarding the possible identity of an object facilitates its recognition from a degraded visual input, though the underlying mechanisms are unclear. Previous work implicated ventral visual cortex but did not disambiguate whether activity-changes in these regions are causal to or merely reflect an effect of facilitated recognition. We used functional magnetic resonance imaging to study top-down influences on processing of gradually revealed objects, by preceding each object with a name that was congruent or incongruent with the object. Congruently primed objects were recognized earlier than incongruently primed, and this was paralleled by shifts in activation profiles for ventral visual, parietal, and prefrontal cortices. Prior to recognition, defined on a trial-by-trial basis, activity in ventral visual cortex rose gradually but equivalently for congruently and incongruently primed objects. In contrast, prerecognition activity was greater with congruent priming in lateral parietal, retrosplenial, and lateral prefrontal cortices, whereas functional coupling between parietal and ventral visual (and also left lateral prefrontal and parietal) cortices was enhanced in the same context. Thus, when controlling for recognition point and stimulus information, activity in ventral visual cortex mirrors recognition success, independent of condition. Facilitation by top-down cues involves lateral parietal cortex interacting with ventral visual areas, potentially explaining why parietal lesions can lead to deficits in recognizing degraded objects even in the context of top-down knowledge.}, address = {UCL Institute of Cognitive Neuroscience \& Department of Psychology, University College London, UK; Wellcome Department of Imaging Neuroscience, University College London, UK.}, author = {Eger, E and Henson, R N N. and Driver, J and Dolan, R J J. }, citeulike-article-id = {954374}, doi = {http://dx.doi.org/10.1093/cercor/bhl119}, issn = {1047-3211}, journal = {Cereb Cortex}, keywords = {attention, heather, joo-seuk, kristina, vision, yigal}, month = {November}, posted-at = {2006-11-21 01:20:43}, priority = {2}, title = {Mechanisms of Top-Down Facilitation in Perception of Visual Objects Studied by fMRI.}, url = {http://dx.doi.org/10.1093/cercor/bhl119}, year = {2006} }

TY - JOUR ID - citeulike:954374 L3 - citeulike-article-id:954374 TI - Mechanisms of Top-Down Facilitation in Perception of Visual Objects Studied by fMRI. JF - Cereb Cortex AD - UCL Institute of Cognitive Neuroscience & Department of Psychology, University College London, UK; Wellcome Department of Imaging Neuroscience, University College London, UK. SN - 1047-3211 N2 - Prior knowledge regarding the possible identity of an object facilitates its recognition from a degraded visual input, though the underlying mechanisms are unclear. Previous work implicated ventral visual cortex but did not disambiguate whether activity-changes in these regions are causal to or merely reflect an effect of facilitated recognition. We used functional magnetic resonance imaging to study top-down influences on processing of gradually revealed objects, by preceding each object with a name that was congruent or incongruent with the object. Congruently primed objects were recognized earlier than incongruently primed, and this was paralleled by shifts in activation profiles for ventral visual, parietal, and prefrontal cortices. Prior to recognition, defined on a trial-by-trial basis, activity in ventral visual cortex rose gradually but equivalently for congruently and incongruently primed objects. In contrast, prerecognition activity was greater with congruent priming in lateral parietal, retrosplenial, and lateral prefrontal cortices, whereas functional coupling between parietal and ventral visual (and also left lateral prefrontal and parietal) cortices was enhanced in the same context. Thus, when controlling for recognition point and stimulus information, activity in ventral visual cortex mirrors recognition success, independent of condition. Facilitation by top-down cues involves lateral parietal cortex interacting with ventral visual areas, potentially explaining why parietal lesions can lead to deficits in recognizing degraded objects even in the context of top-down knowledge. KW - attention KW - heather KW - joo-seuk KW - kristina KW - vision KW - yigal AU - Eger, E AU - Henson, R N AU - Driver, J AU - Dolan, R J PY - 2006/11/13/ UR - http://dx.doi.org/10.1093/cercor/bhl119 ER -