A pathway in primate brain for internal monitoring of movements.

@article{citeulike:937972, abstract = {It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem to frontal cortex might carry corollary discharge signals. We found that neuronal activity in this pathway encodes upcoming eye movements and that inactivating the pathway impairs sequential eye movements consistent with loss of corollary discharge without affecting single eye movements. These results identify a pathway in the brain of the primate Macaca mulatta that conveys corollary discharge signals.}, address = {Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA. mas@lsr.nei.nih.gov}, author = {Sommer, M. A. and Wurtz, R. H. }, citeulike-article-id = {937972}, doi = {10.1126/science.1069590}, issn = {1095-9203}, journal = {Science}, keywords = {corollary\_discharge, electrophysiology, fef, inactivation, mdn, monkey, saccade, spatial\_updating, superiorcolliculus, thalamus}, month = {May}, number = {5572}, pages = {1480--1482}, posted-at = {2006-11-09 16:33:38}, priority = {2}, title = {A pathway in primate brain for internal monitoring of movements.}, url = {http://dx.doi.org/10.1126/science.1069590}, volume = {296}, year = {2002} }

TY - JOUR ID - citeulike:937972 L3 - citeulike-article-id:937972 TI - A pathway in primate brain for internal monitoring of movements. JF - Science VL - 296 IS - 5572 SP - 1480 EP - 1482 AD - Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA. mas@lsr.nei.nih.gov SN - 1095-9203 N2 - It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem to frontal cortex might carry corollary discharge signals. We found that neuronal activity in this pathway encodes upcoming eye movements and that inactivating the pathway impairs sequential eye movements consistent with loss of corollary discharge without affecting single eye movements. These results identify a pathway in the brain of the primate Macaca mulatta that conveys corollary discharge signals. KW - corollary_discharge KW - electrophysiology KW - fef KW - inactivation KW - mdn KW - monkey KW - saccade KW - spatial_updating KW - superiorcolliculus KW - thalamus AU - Sommer, MA AU - Wurtz, RH PY - 2002/05/24/ UR - http://dx.doi.org/10.1126/science.1069590 ER -