Contrast dependence of response normalization in area MT of the rhesus macaque.

@article{citeulike:410109, abstract = {Contrast normalization is a process whereby responses of neurons are scaled according to the total amount of contrast in a region of the image nearby the receptive field of a neuron. This process allows neurons to code for informative scene or object attributes in a manner unaffected by changes in illumination. Evidence for normalization is seen in striate and extrastriate cortex from experiments where multiple stimuli are presented with a single receptive field (RF). Neuronal responses in such experiments are smaller than that predicted by linear summation, revealing the presence of normalization. While the presence of normalization is often clear, its mechanism is less so. To study the mechanism of normalization, we measured the interaction between pairs of brief local stimuli (spatial Gabor functions) within the RFs of cells in the middle temporal (MT or V5) area of monkeys and varied both the location and contrast of the stimuli. We found response summed approximately linearly when contrast was low but rapidly became normalized as stimulus contrast increased. The rapid transition to effective normalization at low contrasts suggested cooperativity in the normalization, and a model embodying such a cooperative step provided a good account of our data.}, address = {Center for Neuroscience and Section of Neurobiology, Physiology, and Behavior, University of California, Davis, California 95616.}, author = {Heuer, H. W. and Britten, K. H. }, citeulike-article-id = {410109}, doi = {http://dx.doi.org/10.1152/jn.00255.2002}, issn = {0022-3077}, journal = {J Neurophysiol}, keywords = {monkey, mt, neurophysiology, normalization}, month = {December}, number = {6}, pages = {3398--3408}, posted-at = {2005-11-28 16:22:12}, priority = {2}, title = {Contrast dependence of response normalization in area MT of the rhesus macaque.}, url = {http://dx.doi.org/10.1152/jn.00255.2002}, volume = {88}, year = {2002} }

TY - JOUR ID - citeulike:410109 L3 - citeulike-article-id:410109 TI - Contrast dependence of response normalization in area MT of the rhesus macaque. JF - J Neurophysiol VL - 88 IS - 6 SP - 3398 EP - 3408 AD - Center for Neuroscience and Section of Neurobiology, Physiology, and Behavior, University of California, Davis, California 95616. SN - 0022-3077 N2 - Contrast normalization is a process whereby responses of neurons are scaled according to the total amount of contrast in a region of the image nearby the receptive field of a neuron. This process allows neurons to code for informative scene or object attributes in a manner unaffected by changes in illumination. Evidence for normalization is seen in striate and extrastriate cortex from experiments where multiple stimuli are presented with a single receptive field (RF). Neuronal responses in such experiments are smaller than that predicted by linear summation, revealing the presence of normalization. While the presence of normalization is often clear, its mechanism is less so. To study the mechanism of normalization, we measured the interaction between pairs of brief local stimuli (spatial Gabor functions) within the RFs of cells in the middle temporal (MT or V5) area of monkeys and varied both the location and contrast of the stimuli. We found response summed approximately linearly when contrast was low but rapidly became normalized as stimulus contrast increased. The rapid transition to effective normalization at low contrasts suggested cooperativity in the normalization, and a model embodying such a cooperative step provided a good account of our data. KW - monkey KW - mt KW - neurophysiology KW - normalization AU - Heuer, HW AU - Britten, KH PY - 2002/12// UR - http://dx.doi.org/10.1152/jn.00255.2002 ER -