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From Thought to Action: The Parietal Cortex as a Bridge between Perception, Action, and Cognition

by: Jacqueline Gottlieb
Neuron, Vol. 53, No. 1. (4 January 2007), pp. 9-16.


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The lateral intraparietal area (LIP) is a subdivision of the inferior parietal lobe that has been implicated in the guidance of spatial attention. In a variety of tasks, LIP provides a "salience representation" of the external world--a topographic visual representation that encodes the locations of salient or behaviorally relevant objects. Recent neurophysiological experiments show that this salience representation incorporates information about multiple behavioral variables--such as a specific motor response, reward, or category membership--associated with the task-relevant object. This integration occurs in a wide variety of tasks, including those requiring eye or limb movements or goal-directed or nontargeting operant responses. Thus, LIP acts as a multifaceted behavioral integrator that binds visuospatial, motor, and cognitive information into a topographically organized signal of behavioral salience. By specifying attentional priority as a synthesis of multiple task demands, LIP operates at the interface of perception, action, and cognition.


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