Integration of data derived from biological variation into the quality management system

@article{citeulike:2965978, abstract = {Backround: Data on within- and between-subject biological variation are available for around 250 analytes commonly used in medical laboratories. Methods: Integration of this data into the quality system occurs at all three levels of laboratory activity: (a) Preanalytic process: biological variation provides the basis for selecting the most appropriate specimen for analysis, for defining sample stability and for deciding suitable timing between samplings; (b) analytic process: biological variation-derived goals are fundamental for designing internal quality control procedures, and for evaluating laboratory performance; and (c) postanalytic process: delta checks based on within-subject biological variation values are used for validating results and for interpreting serial results from a patient. Conclusion: The biological variation is a pillar for managing quality in laboratory medicine.}, author = {Ric\'{o}s, Carmen and Alvarez, Virtudes and Cava, Fernando and Garc\'{i}a-Lario, Jos\'{e} V. and Hern\'{a}ndez, Amparo and Jim\'{e}nez, Carlos V. and Minchinela, Joana and Perich, Carmen and Sim\'{o}n, Margarita }, booktitle = {Quality Specification: From Theory to Practice. Symposium Dedicated to the Memory of Professor Angelo Burlina. International Conference on Laboratory Medicine, Padova, 24 October 2003}, citeulike-article-id = {2965978}, doi = {http://dx.doi.org/10.1016/j.cccn.2004.03.022}, journal = {Clinica Chimica Acta}, keywords = {change, laboratory}, month = {August}, number = {1}, pages = {13--18}, posted-at = {2008-07-05 15:02:10}, priority = {2}, title = {Integration of data derived from biological variation into the quality management system}, url = {http://dx.doi.org/10.1016/j.cccn.2004.03.022}, volume = {346}, year = {2004} }

TY - JOUR ID - citeulike:2965978 L3 - citeulike-article-id:2965978 TI - Integration of data derived from biological variation into the quality management system T2 - Quality Specification: From Theory to Practice. Symposium Dedicated to the Memory of Professor Angelo Burlina. International Conference on Laboratory Medicine, Padova, 24 October 2003 JF - Clinica Chimica Acta VL - 346 IS - 1 SP - 13 EP - 18 N2 - Backround: Data on within- and between-subject biological variation are available for around 250 analytes commonly used in medical laboratories. Methods: Integration of this data into the quality system occurs at all three levels of laboratory activity: (a) Preanalytic process: biological variation provides the basis for selecting the most appropriate specimen for analysis, for defining sample stability and for deciding suitable timing between samplings; (b) analytic process: biological variation-derived goals are fundamental for designing internal quality control procedures, and for evaluating laboratory performance; and (c) postanalytic process: delta checks based on within-subject biological variation values are used for validating results and for interpreting serial results from a patient. Conclusion: The biological variation is a pillar for managing quality in laboratory medicine. KW - change KW - laboratory AU - Ricós, Carmen AU - Alvarez, Virtudes AU - Cava, Fernando AU - García-Lario, José AU - Hernández, Amparo AU - Jiménez, Carlos AU - Minchinela, Joana AU - Perich, Carmen AU - Simón, Margarita PY - 2004/08/02/ UR - http://dx.doi.org/10.1016/j.cccn.2004.03.022 ER -