Polycystic Ovary Syndrome: Diagnosis and Treatment

@article{citeulike:2807664, abstract = {Polycystic ovary syndrome affects 6\%-7\% of reproductive-aged women, making it the most common endocrine disorder in this population. It is characterized by chronic anovulation and hyperandrogenism. Affected women may present with reproductive manifestations such as irregular menses or infertility, or cutaneous manifestations, including hirsutism, acne, or male-pattern hair loss. Over the past decade, several serious metabolic complications also have been associated with polycystic ovary syndrome including type 2 diabetes mellitus, metabolic syndrome, sleep apnea, and possibly cardiovascular disease and nonalcoholic fatty liver disease. In addition to treating symptoms by regulating menstrual cycles and improving hyperandrogenism, it is imperative that clinicians recognize and treat metabolic complications. Lifestyle therapies are first-line treatment in women with polycystic ovary syndrome, particularly if they are overweight. Pharmacological therapies are also available and should be tailored on an individual basis. This article reviews the diagnosis, clinical manifestations, metabolic complications, and treatment of the syndrome. A table summarizing treatment recommendations is provided.}, author = {Setji, Tracy L. and Brown, Ann J. }, citeulike-article-id = {2807664}, doi = {10.1016/j.amjmed.2006.06.029}, journal = {The American Journal of Medicine}, month = {February}, number = {2}, pages = {128--132}, posted-at = {2008-05-17 14:57:03}, priority = {2}, title = {Polycystic Ovary Syndrome: Diagnosis and Treatment}, url = {http://dx.doi.org/10.1016/j.amjmed.2006.06.029}, volume = {120}, year = {2007} }

TY - JOUR ID - citeulike:2807664 L3 - citeulike-article-id:2807664 TI - Polycystic Ovary Syndrome: Diagnosis and Treatment JF - The American Journal of Medicine VL - 120 IS - 2 SP - 128 EP - 132 N2 - Polycystic ovary syndrome affects 6%-7% of reproductive-aged women, making it the most common endocrine disorder in this population. It is characterized by chronic anovulation and hyperandrogenism. Affected women may present with reproductive manifestations such as irregular menses or infertility, or cutaneous manifestations, including hirsutism, acne, or male-pattern hair loss. Over the past decade, several serious metabolic complications also have been associated with polycystic ovary syndrome including type 2 diabetes mellitus, metabolic syndrome, sleep apnea, and possibly cardiovascular disease and nonalcoholic fatty liver disease. In addition to treating symptoms by regulating menstrual cycles and improving hyperandrogenism, it is imperative that clinicians recognize and treat metabolic complications. Lifestyle therapies are first-line treatment in women with polycystic ovary syndrome, particularly if they are overweight. Pharmacological therapies are also available and should be tailored on an individual basis. This article reviews the diagnosis, clinical manifestations, metabolic complications, and treatment of the syndrome. A table summarizing treatment recommendations is provided. AU - Setji, Tracy AU - Brown, Ann PY - 2007/02// UR - http://dx.doi.org/10.1016/j.amjmed.2006.06.029 ER -