Infectious Complications in Renal Transplant Recipients

@article{citeulike:2806730, abstract = {Post-kidney transplant infection is the most common life-threatening complication of long-term immunosuppressive therapy. Optimal immunosuppression, in which a balance is maintained between prevention of rejection and avoidance of infection, is the most challenging aspect of posttransplantation care. The study of infectious complications in immunologically compromised recipients is changing rapidly, particularly in the fields of prophylactic and preemptive strategies, molecular diagnostic methods, and antimicrobial agents. In addition, emerging pathogens such as BK polyomavirus and West Nile flavivirus infections and the introduction of newer immunosuppressive agents that constantly change the risk profiles for opportunistic infections has added layers of complexity to this burgeoning field. Although remarkable progress has been made in these disciplines, comprehensive understanding of the clinical manifestations of infections remains limited, and the standardization of prophylaxis, diagnosis, and treatment of most infections is yet inadequately defined. The long-term goal for optimal care of transplant recipients, with respect to infection, is the prevention and/or early recognition and treatment of infections while avoiding drug-related toxicities.}, author = {Parasuraman, Ravi and Yee, Jerry and Karthikeyan, Vanji and Del}, booktitle = {Infectious Complications in Patients with Chronic Kidney Disease}, citeulike-article-id = {2806730}, doi = {10.1053/j.ackd.2006.04.008}, journal = {Advances in Chronic Kidney Disease}, month = {July}, number = {3}, pages = {280--294}, posted-at = {2008-05-17 11:01:06}, priority = {2}, title = {Infectious Complications in Renal Transplant Recipients}, url = {http://dx.doi.org/10.1053/j.ackd.2006.04.008}, volume = {13}, year = {2006} }

TY - JOUR ID - citeulike:2806730 L3 - citeulike-article-id:2806730 TI - Infectious Complications in Renal Transplant Recipients T2 - Infectious Complications in Patients with Chronic Kidney Disease JF - Advances in Chronic Kidney Disease VL - 13 IS - 3 SP - 280 EP - 294 N2 - Post-kidney transplant infection is the most common life-threatening complication of long-term immunosuppressive therapy. Optimal immunosuppression, in which a balance is maintained between prevention of rejection and avoidance of infection, is the most challenging aspect of posttransplantation care. The study of infectious complications in immunologically compromised recipients is changing rapidly, particularly in the fields of prophylactic and preemptive strategies, molecular diagnostic methods, and antimicrobial agents. In addition, emerging pathogens such as BK polyomavirus and West Nile flavivirus infections and the introduction of newer immunosuppressive agents that constantly change the risk profiles for opportunistic infections has added layers of complexity to this burgeoning field. Although remarkable progress has been made in these disciplines, comprehensive understanding of the clinical manifestations of infections remains limited, and the standardization of prophylaxis, diagnosis, and treatment of most infections is yet inadequately defined. The long-term goal for optimal care of transplant recipients, with respect to infection, is the prevention and/or early recognition and treatment of infections while avoiding drug-related toxicities. AU - Parasuraman, Ravi AU - Yee, Jerry AU - Karthikeyan, Vanji AU - Del PY - 2006/07// UR - http://dx.doi.org/10.1053/j.ackd.2006.04.008 ER -