Pathogenomics of helicobacter.

by: C Josenhans, D Beier, B Linz, TF Meyer, S Suerbaum

Int J Med Microbiol, Vol. 297, No. 7-8. (November 2007), pp. 589-600.

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Abstract

The pathogenic bacterium Helicobacter pylori infects half of the human population and is one of the genetically most diverse bacterial species known. H. pylori was one of the first bacterial species whose genome was sequenced in 1997, and the first species for which two complete sequences from independent isolates were available for within-species comparisons. For almost 10 years, genomic and post-genomic analysis has contributed enormously to our understanding of the pathogenesis of H. pylori infection. This review summarizes the available information, emphasizing work performed in the framework of the PathoGenoMik funding initiative (2001-2006) of the German Ministry of Education and Research.

@article{citeulike:2548383, abstract = {The pathogenic bacterium Helicobacter pylori infects half of the human population and is one of the genetically most diverse bacterial species known. H. pylori was one of the first bacterial species whose genome was sequenced in 1997, and the first species for which two complete sequences from independent isolates were available for within-species comparisons. For almost 10 years, genomic and post-genomic analysis has contributed enormously to our understanding of the pathogenesis of H. pylori infection. This review summarizes the available information, emphasizing work performed in the framework of the PathoGenoMik funding initiative (2001-2006) of the German Ministry of Education and Research.}, address = {Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Carl-Neuberg-Street 1, D-30625 Hannover, Germany.}, author = {Josenhans, C. and Beier, D. and Linz, B. and Meyer, T. F. and Suerbaum, S. }, citeulike-article-id = {2548383}, doi = {10.1016/j.ijmm.2007.02.006}, issn = {1438-4221}, journal = {Int J Med Microbiol}, month = {November}, number = {7-8}, pages = {589--600}, posted-at = {2008-03-18 04:37:01}, priority = {2}, title = {Pathogenomics of helicobacter.}, url = {http://dx.doi.org/10.1016/j.ijmm.2007.02.006}, volume = {297}, year = {2007} }

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TY - JOUR ID - citeulike:2548383 L3 - citeulike-article-id:2548383 TI - Pathogenomics of helicobacter. JF - Int J Med Microbiol VL - 297 IS - 7-8 SP - 589 EP - 600 AD - Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Carl-Neuberg-Street 1, D-30625 Hannover, Germany. SN - 1438-4221 N2 - The pathogenic bacterium Helicobacter pylori infects half of the human population and is one of the genetically most diverse bacterial species known. H. pylori was one of the first bacterial species whose genome was sequenced in 1997, and the first species for which two complete sequences from independent isolates were available for within-species comparisons. For almost 10 years, genomic and post-genomic analysis has contributed enormously to our understanding of the pathogenesis of H. pylori infection. This review summarizes the available information, emphasizing work performed in the framework of the PathoGenoMik funding initiative (2001-2006) of the German Ministry of Education and Research. AU - Josenhans, C AU - Beier, D AU - Linz, B AU - Meyer, TF AU - Suerbaum, S PY - 2007/11// UR - http://dx.doi.org/10.1016/j.ijmm.2007.02.006 ER -

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