Portal hypertension Pre-primary and primary prophylaxis of variceal bleeding.

@article{citeulike:2517376, abstract = {In liver cirrhosis, variceal bleeding is the last in a chain of events initiated by the increase in portal pressure (estimated in clinical practice by the hepatic venous pressure gradient). When hepatic venous pressure gradient goes above 10mmHg the patient is at risk of developing varices, and when hepatic venous pressure gradient reaches 12mmHg variceal bleeding might develop. Currently, there is not any effective therapy for the prevention of the development of varices. When varices are small, beta-adrenergic blockers might prevent the enlargement of the varices, and may reduce the risk of variceal bleeding. In patients with medium to large varices, beta-blockers are clearly effective in reducing the risk of variceal bleeding. Endoscopic band ligation might be more effective than beta-blockers, but available evidence is still very weak.}, address = {Hepatic Hemodynamic Laboratory, Liver Unit, Institut d’Investigacions Biom\`{e}diques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigaci\'{o}n Biom\'{e}dica en Red de Enfermedades Hep\'{a}ticas y Digestivas (Ciberehd), Spain.}, author = {Tiani, C and Abraldes, J G G. and Bosch, J }, citeulike-article-id = {2517376}, doi = {http://dx.doi.org/10.1016/j.dld.2007.12.004}, issn = {1590-8658}, journal = {Dig Liver Dis}, month = {February}, posted-at = {2008-03-12 02:02:51}, priority = {2}, title = {Portal hypertension Pre-primary and primary prophylaxis of variceal bleeding.}, url = {http://dx.doi.org/10.1016/j.dld.2007.12.004}, year = {2008} }

TY - JOUR ID - citeulike:2517376 L3 - citeulike-article-id:2517376 TI - Portal hypertension Pre-primary and primary prophylaxis of variceal bleeding. JF - Dig Liver Dis AD - Hepatic Hemodynamic Laboratory, Liver Unit, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Spain. SN - 1590-8658 N2 - In liver cirrhosis, variceal bleeding is the last in a chain of events initiated by the increase in portal pressure (estimated in clinical practice by the hepatic venous pressure gradient). When hepatic venous pressure gradient goes above 10mmHg the patient is at risk of developing varices, and when hepatic venous pressure gradient reaches 12mmHg variceal bleeding might develop. Currently, there is not any effective therapy for the prevention of the development of varices. When varices are small, beta-adrenergic blockers might prevent the enlargement of the varices, and may reduce the risk of variceal bleeding. In patients with medium to large varices, beta-blockers are clearly effective in reducing the risk of variceal bleeding. Endoscopic band ligation might be more effective than beta-blockers, but available evidence is still very weak. AU - Tiani, C AU - Abraldes, J G AU - Bosch, J PY - 2008/02/19/ UR - http://dx.doi.org/10.1016/j.dld.2007.12.004 ER -