Measuring apoptosis at the single cell level

@article{citeulike:2459214, abstract = {The use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potential changes, translocation of Bcl-2 family members, caspase activation, phosphatidylserine flip and plasma membrane rupture. We discuss these techniques here and highlight the advantages and drawbacks of using such approaches to study apoptosis.}, author = {Bouchier-Hayes, Lisa and Munoz-Pinedo, Cristina and Connell, Samuel and Green, Douglas R. }, booktitle = {Apoptosis}, citeulike-article-id = {2459214}, doi = {10.1016/j.ymeth.2007.11.007}, journal = {Methods}, month = {March}, number = {3}, pages = {222--228}, posted-at = {2008-03-03 03:25:26}, priority = {2}, title = {Measuring apoptosis at the single cell level}, url = {http://dx.doi.org/10.1016/j.ymeth.2007.11.007}, volume = {44}, year = {2008} }

TY - JOUR ID - citeulike:2459214 L3 - citeulike-article-id:2459214 TI - Measuring apoptosis at the single cell level T2 - Apoptosis JF - Methods VL - 44 IS - 3 SP - 222 EP - 228 N2 - The use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potential changes, translocation of Bcl-2 family members, caspase activation, phosphatidylserine flip and plasma membrane rupture. We discuss these techniques here and highlight the advantages and drawbacks of using such approaches to study apoptosis. AU - Bouchier-Hayes, Lisa AU - Munoz-Pinedo, Cristina AU - Connell, Samuel AU - Green, Douglas PY - 2008/03// UR - http://dx.doi.org/10.1016/j.ymeth.2007.11.007 ER -