ChemBank: a small-molecule screening and cheminformatics resource database

@article{citeulike:2100159, abstract = {ChemBank (http://chembank.broad.harvard.edu/) is a public, web-based informatics environment developed through a collaboration between the Chemical Biology Program and Platform at the Broad Institute of Harvard and MIT. This knowledge environment includes freely available data derived from small molecules and small-molecule screens and resources for studying these data. ChemBank is unique among small-molecule databases in its dedication to the storage of raw screening data, its rigorous definition of screening experiments in terms of statistical hypothesis testing, and its metadata-based organization of screening experiments into projects involving collections of related assays. ChemBank stores an increasingly varied set of measurements derived from cells and other biological assay systems treated with small molecules. Analysis tools are available and are continuously being developed that allow the relationships between small molecules, cell measurements, and cell states to be studied. Currently, ChemBank stores information on hundreds of thousands of small molecules and hundreds of biomedically relevant assays that have been performed at the Broad Institute by collaborators from the worldwide research community. The goal of ChemBank is to provide life scientists unfettered access to biomedically relevant data and tools heretofore available primarily in the private sector. 10.1093/nar/gkm843}, author = {Seiler, Kathleen P. and George, Gregory A. and Happ, Mary P. and Bodycombe, Nicole E. and Carrinski, Hyman A. and Norton, Stephanie and Brudz, Steve and Sullivan, John P. and Muhlich, Jeremy and Serrano, Martin and Ferraiolo, Paul and Tolliday, Nicola J. and Schreiber, Stuart L. and Clemons, Paul A. }, citeulike-article-id = {2100159}, doi = {http://dx.doi.org/10.1093/nar/gkm843}, journal = {Nucl. Acids Res.}, keywords = {database, drug}, month = {October}, pages = {gkm843+}, posted-at = {2008-05-24 02:16:24}, priority = {2}, title = {ChemBank: a small-molecule screening and cheminformatics resource database}, url = {http://dx.doi.org/10.1093/nar/gkm843}, year = {2007} }

TY - JOUR ID - citeulike:2100159 L3 - citeulike-article-id:2100159 TI - ChemBank: a small-molecule screening and cheminformatics resource database JF - Nucl. Acids Res. SP - gkm843 N2 - ChemBank (http://chembank.broad.harvard.edu/) is a public, web-based informatics environment developed through a collaboration between the Chemical Biology Program and Platform at the Broad Institute of Harvard and MIT. This knowledge environment includes freely available data derived from small molecules and small-molecule screens and resources for studying these data. ChemBank is unique among small-molecule databases in its dedication to the storage of raw screening data, its rigorous definition of screening experiments in terms of statistical hypothesis testing, and its metadata-based organization of screening experiments into projects involving collections of related assays. ChemBank stores an increasingly varied set of measurements derived from cells and other biological assay systems treated with small molecules. Analysis tools are available and are continuously being developed that allow the relationships between small molecules, cell measurements, and cell states to be studied. Currently, ChemBank stores information on hundreds of thousands of small molecules and hundreds of biomedically relevant assays that have been performed at the Broad Institute by collaborators from the worldwide research community. The goal of ChemBank is to provide life scientists unfettered access to biomedically relevant data and tools heretofore available primarily in the private sector. 10.1093/nar/gkm843 KW - database KW - drug AU - Seiler, Kathleen AU - George, Gregory AU - Happ, Mary AU - Bodycombe, Nicole AU - Carrinski, Hyman AU - Norton, Stephanie AU - Brudz, Steve AU - Sullivan, John AU - Muhlich, Jeremy AU - Serrano, Martin AU - Ferraiolo, Paul AU - Tolliday, Nicola AU - Schreiber, Stuart AU - Clemons, Paul PY - 2007/10/18/ UR - http://dx.doi.org/10.1093/nar/gkm843 ER -