OMA Browser - Exploring orthologous relations across 352 complete genomes.

by: Adrian Schneider, Christophe Dessimoz, Gaston H H Gonnet

Bioinformatics (1 June 2007)

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Abstract

MOTIVATION: Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale efforts with various methodologies and scope tackle this problem, including OMA (the Orthologous MAtrix project). RESULTS: Based on the results of the OMA project, we introduce here the OMA Browser, a web-based tool allowing the exploration of orthologous relations over 352 complete genomes. Orthologs can be viewed as groups across species, but also at the level of sequence pairs, allowing the distinction among one-to-one, one-to-many and many-to-many orthologs. AVAILABILITY: http://omabrowser.org.

@article{citeulike:1368859, abstract = {MOTIVATION: Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale efforts with various methodologies and scope tackle this problem, including OMA (the Orthologous MAtrix project). RESULTS: Based on the results of the OMA project, we introduce here the OMA Browser, a web-based tool allowing the exploration of orthologous relations over 352 complete genomes. Orthologs can be viewed as groups across species, but also at the level of sequence pairs, allowing the distinction among one-to-one, one-to-many and many-to-many orthologs. AVAILABILITY: http://omabrowser.org.}, address = {Institute of Computational Science, Informatik, ETH Zurich, Switzerland.}, author = {Schneider, Adrian and Dessimoz, Christophe and Gonnet, Gaston H H. }, citeulike-article-id = {1368859}, issn = {1460-2059}, journal = {Bioinformatics}, month = {June}, posted-at = {2008-01-26 03:09:32}, priority = {2}, title = {OMA Browser - Exploring orthologous relations across 352 complete genomes.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/17545180}, year = {2007} }

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TY - JOUR ID - citeulike:1368859 L3 - citeulike-article-id:1368859 TI - OMA Browser - Exploring orthologous relations across 352 complete genomes. JF - Bioinformatics AD - Institute of Computational Science, Informatik, ETH Zurich, Switzerland. SN - 1460-2059 N2 - MOTIVATION: Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale efforts with various methodologies and scope tackle this problem, including OMA (the Orthologous MAtrix project). RESULTS: Based on the results of the OMA project, we introduce here the OMA Browser, a web-based tool allowing the exploration of orthologous relations over 352 complete genomes. Orthologs can be viewed as groups across species, but also at the level of sequence pairs, allowing the distinction among one-to-one, one-to-many and many-to-many orthologs. AVAILABILITY: http://omabrowser.org. AU - Schneider, Adrian AU - Dessimoz, Christophe AU - Gonnet, Gaston H PY - 2007/06/01/ UR - http://view.ncbi.nlm.nih.gov/pubmed/17545180 ER -

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