Receptive fields in human visual cortex mapped with surface electrodes.

@article{citeulike:1642471, abstract = {Most of our understanding of the functional organization of human visual cortex comes from lesion and functional imaging studies and by extrapolation from results obtained by neuroanatomical and neurophysiological studies in nonhuman primates. Although some single-unit and field potential recordings have been made in human visual cortex, none has provided quantitative characterization of spatial receptive fields (RFs) of individual sites. Here we use subdural electrodes implanted for clinical purposes to quantitatively measure response properties in different regions of human visual cortex. We find significant differences in RF size, response latency, and response magnitude for sites in early visual areas, versus sites in later stages of both the dorsal and ventral streams. In addition, we use this technique to estimate the cortical magnification factor in early human visual cortex. The spatial and temporal resolution of cortical surface recordings suggest that this technique is well suited to examine further issues in visual processing in humans.}, address = {Department of Neurosurgery, Baylor College of Medicine, One Baylor Plaza, S-603, Houston, TX 77030, USA.}, author = {Yoshor, D. and Bosking, W. H. and Ghose, G. M. and Maunsell, J. H. }, citeulike-article-id = {1642471}, comment = {Using subdural electrodes implanted in human patients with medically intractable epilepsy, Yoshor et al. mapped the receptive fields of various areas in visual cortex, namely V1-V2, V3-V4, MT, and areas of the ventral stream beyond V4. Corroborating evidence from DiCarlo and Maunsell concerning the RFs of IT neurons, they found small and well-defined RFs that were not significantly larger than those found in V4, though it is uncertain if some of the recordings they believed to be in IT were actually taken from ventral V4. Overall, they found that RF size and latency increases along the ventral pathway. The mapping stimuli utilized were checkerboard patterns, which may have some bearing on the size of the measured RFs, especially in areas beyond V4. }, doi = {http://dx.doi.org/10.1093/cercor/bhl138}, issn = {1047-3211}, journal = {Cereb Cortex}, keywords = {electrophysiology, extrastriate, it, physiology, receptive-field, v1, v2, v4, ventral}, month = {October}, number = {10}, pages = {2293--2302}, posted-at = {2008-07-03 22:39:52}, priority = {0}, title = {Receptive fields in human visual cortex mapped with surface electrodes.}, url = {http://dx.doi.org/10.1093/cercor/bhl138}, volume = {17}, year = {2007} }

TY - JOUR ID - citeulike:1642471 L3 - citeulike-article-id:1642471 TI - Receptive fields in human visual cortex mapped with surface electrodes. JF - Cereb Cortex VL - 17 IS - 10 SP - 2293 EP - 2302 AD - Department of Neurosurgery, Baylor College of Medicine, One Baylor Plaza, S-603, Houston, TX 77030, USA. SN - 1047-3211 N2 - Most of our understanding of the functional organization of human visual cortex comes from lesion and functional imaging studies and by extrapolation from results obtained by neuroanatomical and neurophysiological studies in nonhuman primates. Although some single-unit and field potential recordings have been made in human visual cortex, none has provided quantitative characterization of spatial receptive fields (RFs) of individual sites. Here we use subdural electrodes implanted for clinical purposes to quantitatively measure response properties in different regions of human visual cortex. We find significant differences in RF size, response latency, and response magnitude for sites in early visual areas, versus sites in later stages of both the dorsal and ventral streams. In addition, we use this technique to estimate the cortical magnification factor in early human visual cortex. The spatial and temporal resolution of cortical surface recordings suggest that this technique is well suited to examine further issues in visual processing in humans. KW - electrophysiology KW - extrastriate KW - it KW - physiology KW - receptive-field KW - v1 KW - v2 KW - v4 KW - ventral N1 - Using subdural electrodes implanted in human patients with medically intractable epilepsy, Yoshor et al. mapped the receptive fields of various areas in visual cortex, namely V1-V2, V3-V4, MT, and areas of the ventral stream beyond V4. Corroborating evidence from DiCarlo and Maunsell concerning the RFs of IT neurons, they found small and well-defined RFs that were not significantly larger than those found in V4, though it is uncertain if some of the recordings they believed to be in IT were actually taken from ventral V4. Overall, they found that RF size and latency increases along the ventral pathway. The mapping stimuli utilized were checkerboard patterns, which may have some bearing on the size of the measured RFs, especially in areas beyond V4. AU - Yoshor, D AU - Bosking, WH AU - Ghose, GM AU - Maunsell, JH PY - 2007/10// UR - http://dx.doi.org/10.1093/cercor/bhl138 ER -