DNA microarrays in clinical cancer research.

by: R Wadlow, S Ramaswamy

Current molecular medicine, Vol. 5, No. 1. (February 2005), pp. 111-120.

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microarray_technology, review

Abstract

The recent sequencing of the human genome, coupled with advances in biotechnology, is enabling the comprehensive molecular "profiling" of human tissues. In particular, DNA microarrays are powerful tools for obtaining global views of human tumor gene expression. Complex information from tumor "expression profiling" studies can, in turn, be used to create novel molecular cancer diagnostics. We discuss the utility of DNA microarray-based tumor profiling in clinical cancer research, highlight some important recent studies, and identify future avenues of research in this evolving field.

@article{citeulike:3024440, abstract = {The recent sequencing of the human genome, coupled with advances in biotechnology, is enabling the comprehensive molecular "profiling" of human tissues. In particular, DNA microarrays are powerful tools for obtaining global views of human tumor gene expression. Complex information from tumor "expression profiling" studies can, in turn, be used to create novel molecular cancer diagnostics. We discuss the utility of DNA microarray-based tumor profiling in clinical cancer research, highlight some important recent studies, and identify future avenues of research in this evolving field.}, address = {Massachusetts General Hospital Cancer Center \& Harvard Medical School, MA, USA.}, author = {Wadlow, R. and Ramaswamy, S. }, citeulike-article-id = {3024440}, issn = {1566-5240}, journal = {Current molecular medicine}, keywords = {microarray\_technology, review}, month = {February}, number = {1}, pages = {111--120}, posted-at = {2008-07-21 14:36:35}, priority = {0}, title = {DNA microarrays in clinical cancer research.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15720274}, volume = {5}, year = {2005} }

RIS record

TY - JOUR ID - citeulike:3024440 L3 - citeulike-article-id:3024440 TI - DNA microarrays in clinical cancer research. JF - Current molecular medicine VL - 5 IS - 1 SP - 111 EP - 120 AD - Massachusetts General Hospital Cancer Center & Harvard Medical School, MA, USA. SN - 1566-5240 N2 - The recent sequencing of the human genome, coupled with advances in biotechnology, is enabling the comprehensive molecular "profiling" of human tissues. In particular, DNA microarrays are powerful tools for obtaining global views of human tumor gene expression. Complex information from tumor "expression profiling" studies can, in turn, be used to create novel molecular cancer diagnostics. We discuss the utility of DNA microarray-based tumor profiling in clinical cancer research, highlight some important recent studies, and identify future avenues of research in this evolving field. KW - microarray_technology KW - review AU - Wadlow, R AU - Ramaswamy, S PY - 2005/02// UR - http://view.ncbi.nlm.nih.gov/pubmed/15720274 ER -

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