A lexicon for homeodomain-DNA recognition.

by: M Affolter, M Slattery, RS Mann

Cell, Vol. 133, No. 7. (27 June 2008), pp. 1133-1135.

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Abstract

Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

@article{citeulike:2976694, abstract = {Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.}, address = {Growth and Development, Biozentrum der Universit\"{a}t Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland. markus.affolter@unibas.ch}, author = {Affolter, M. and Slattery, M. and Mann, R. S. }, citeulike-article-id = {2976694}, doi = {http://dx.doi.org/10.1016/j.cell.2008.06.008}, issn = {1097-4172}, journal = {Cell}, keywords = {transcription, wide\_mapping}, month = {June}, number = {7}, pages = {1133--1135}, posted-at = {2008-07-23 18:46:36}, priority = {2}, title = {A lexicon for homeodomain-DNA recognition.}, url = {http://dx.doi.org/10.1016/j.cell.2008.06.008}, volume = {133}, year = {2008} }

RIS record

TY - JOUR ID - citeulike:2976694 L3 - citeulike-article-id:2976694 TI - A lexicon for homeodomain-DNA recognition. JF - Cell VL - 133 IS - 7 SP - 1133 EP - 1135 AD - Growth and Development, Biozentrum der Universität Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland. markus.affolter@unibas.ch SN - 1097-4172 N2 - Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo. KW - transcription KW - wide_mapping AU - Affolter, M AU - Slattery, M AU - Mann, RS PY - 2008/06/27/ UR - http://dx.doi.org/10.1016/j.cell.2008.06.008 ER -

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