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higueruelo sm [178 articles]

最近 higueruelo さんのライブラリに追加された論文の中から タグ sm. You can also see everyone's sm.
  • The unfoldomics decade: an update on intrinsically disordered proteins.
    BMC genomics, Vol. 9 Suppl 2 (2008)
    by AK Dunker, CJ Oldfield, J Meng, P Romero, JY Yang, JW Chen, V Vacic, Z Obradovic, VN Uversky
    posted to xf sm review ppi disorder 2008 by higueruelo on 2008-10-13 15:02:38 as *** along with 3 people carlosjavierna jyuh chad_davis
  • Discovery of an Orally Bioavailable Small Molecule Inhibitor of Prosurvival B-Cell Lymphoma 2 Proteins
    J. Med. Chem. (8 October 2008)
    by Cheol-Min Park, Milan Bruncko, Jessica Adickes, Joy Bauch, Hong Ding, Aaron Kunzer, Kennan C Marsh, Paul Nimmer, Alexander R Shoemaker, Xiaohong Song, Stephen K Tahir, Christin Tse, Xilu Wang, Michael D Wendt, Xiufen Yang, Haichao Zhang, Stephen W Fesik, Saul H Rosenberg, Steven W Elmore
    posted to xf sm ppi bcl2 abbott 2008 by higueruelo on 2008-10-08 14:05:02 as ***
  • Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy.
    Annual review of pharmacology and toxicology (3 October 2008)
    by Sanjeev Shangary, Shaomeng Wang
    posted to xf sm review ppi p53 mdm2 2008 by higueruelo on 2008-10-07 23:36:18 as ***
  • Disrupting the Rb-Raf-1 interaction: A potential therapeutic target for cancer.
    Drug news & perspectives, Vol. 21, No. 6. (g 2008), pp. 331-335.
    by RK Davis, S Chellappan
    posted to xf sm raf1 ppi 2008 by higueruelo on 2008-10-07 23:34:35 as ***
  • A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.
    Cancer research, Vol. 68, No. 10. (15 May 2008), pp. 3810-3818.
    by R Kinkade, P Dasgupta, A Carie, D Pernazza, M Carless, S Pillai, N Lawrence, SM Sebti, S Chellappan
    posted to xf sm raf1 ppi 2008 by higueruelo on 2008-10-07 23:32:41 as ***
  • Approved Drug Mimics of Short Peptide Ligands from Protein Interaction Motifs.
    Journal of chemical information and modeling (1 October 2008)
    by Laavanya Parthasarathi, Fergal Casey, Amelie Stein, Patrick Aloy, Denis C Shields
    posted to xf sm ppi peptidomimetics drugs 2008 by higueruelo on 2008-10-05 12:15:08 as ***
  • A Novel Class of Small Molecule Inhibitors of Hsp90
    ACS Chem. Biol. (12 September 2008)
    by Fang Yi, Lynne Regan
    posted to xf sm ppi hsp90 hop 2008 by higueruelo on 2008-09-24 14:23:52 as ***
  • Small-molecule inhibition of HIV-1 Vif.
    Nature biotechnology (21 September 2008)
    by Robin Nathans, Hong Cao, Natalia Sharova, Akbar Ali, Mark Sharkey, Ruzena Stranska, Mario Stevenson, Tariq M M Rana
    posted to xf sm ppi hiv1 2008 by higueruelo on 2008-09-24 14:19:00 as *** along with 2 people adib kieran101
  • Characterization of the Binding Site for Inhibitors of the HPV11 E1-E2 Protein Interaction on the E2 Transactivation Domain by Photoaffinity Labeling and Mass Spectrometry
    Anal. Chem., Vol. 76, No. 7. (1 April 2004), pp. 2095-2102.
    by W Davidson, GA Mcgibbon, PW White, C Yoakim, JL Hopkins, I Guse, DM Hambly, L Frego, WW Ogilvie, P Lavallee, J Archambault
    posted to sm ppi intimbal e2 e1 2004 by higueruelo on 2008-09-24 11:05:30 as read
  • Small Molecule Protein–Protein Interaction Inhibitors as CNS Therapeutic Agents: Current Progress and Future Hurdles
    Neuropsychopharmacology, Vol. aop, No. current.
    by Levi L Blazer, Richard R Neubig
    posted to xf sm review ppi cns 2008 by higueruelo on 2008-09-19 13:44:58 as ***
  • A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor [see commetns]
    Science (New York, N.Y.), Vol. 281, No. 5374. (10 July 1998), pp. 257-259.
    by SS Tian, P Lamb, AG King, SG Miller, L Kessler, JI Luengo, L Averill, RK Johnson, JG Gleason, LM Pelus, SB Dillon, J Rosen
    posted to xf sm ppi gcsfr 1998 by higueruelo on 2008-09-12 15:55:35 as ***
  • Selective binding and oligomerization of the murine granulocyte colony-stimulating factor receptor by a low molecular weight, nonpeptidyl ligand.
    The Journal of biological chemistry, Vol. 278, No. 11. (14 March 2003), pp. 9426-9434.
    by ML Doyle, SS Tian, SG Miller, L Kessler, AE Baker, MR Brigham-Burke, SB Dillon, KJ Duffy, RM Keenan, R Lehr, J Rosen, LA Schneeweis, J Trill, PR Young, JI Luengo, P Lamb
    posted to xf sm ppi gcsfr 2003 by higueruelo on 2008-09-12 15:55:05 as ***
  • Suppression of cancer cachexia by 20S,21-epoxy-resibufogenin-3-acetate-a novel nonpeptide IL-6 receptor antagonist.
    Biochemical and biophysical research communications, Vol. 323, No. 3. (22 October 2004), pp. 1096-1102.
    by A Enomoto, MC Rho, A Fukami, O Hiraku, K Komiyama, M Hayashi
    posted to xf sm ppi il6 2004 by higueruelo on 2008-09-12 15:51:23 as ***
  • Biological activity of a novel nonpeptide antagonist to the interleukin-6 receptor 20S,21-epoxy-resibufogenin-3-formate.
    The Journal of pharmacology and experimental therapeutics, Vol. 303, No. 1. (October 2002), pp. 104-109.
    by M Hayashi, MC Rho, A Fukami, A Enomoto, S Nonaka, Y Sekiguchi, T Yanagisawa, A Yamashita, T Nogawa, Y Kamano, K Komiyama
    posted to xf sm ppi il6 2002 by higueruelo on 2008-09-12 15:49:57 as ***
  • Development of IL-5 receptor antagonists.
    Current pharmaceutical design, Vol. 8, No. 20. (2002), pp. 1837-1844.
    by I Uings, M McKinnon
    posted to xf sm review ppi peptidomimetics il5 2002 by higueruelo on 2008-09-12 15:46:23 as ***
  • Cytokine receptor dimerization and activation: prospects for small molecule agonists.
    Bioorganic & medicinal chemistry, Vol. 9, No. 3. (March 2001), pp. 557-562.
    by DL Boger, J Goldberg
    posted to xf sm review ppi epo 2001 by higueruelo on 2008-09-12 14:20:11 as ***
  • Xanthocillins as thrombopoietin mimetic small molecules.
    Bioorganic & medicinal chemistry, Vol. 13, No. 23. (1 December 2005), pp. 6388-6393.
    by R Sakai, T Nakamura, T Nishino, M Yamamoto, A Miyamura, H Miyamoto, N Ishiwata, N Komatsu, H Kamiya, N Tsuruzoe
    posted to xf tpo sm ppi 2005 by higueruelo on 2008-09-12 14:16:11 as ***
  • New benzimidazoles as thrombopoietin receptor agonists.
    Bioorganic & medicinal chemistry letters, Vol. 16, No. 5. (1 March 2006), pp. 1212-1216.
    by IG Safonov, DA Heerding, RM Keenan, AT Price, CL Erickson-Miller, CB Hopson, JL Levin, KA Lord, PM Tapley
    posted to xf tpo sm ppi 2006 by higueruelo on 2008-09-12 14:15:27 as ***
  • NMR structural studies of interactions of a small, nonpeptidyl Tpo mimic with the thrombopoietin receptor extracellular juxtamembrane and transmembrane domains.
    The Journal of biological chemistry, Vol. 282, No. 19. (11 May 2007), pp. 14253-14261.
    by MJ Kim, SH Park, SJ Opella, TH Marsilje, PY Michellys, HM Seidel, SS Tian
    posted to xf tpo struct-determination sm ppi nmr 2007 by higueruelo on 2008-09-12 14:10:35 as ***
  • Discovery and biological evaluation of benzo[a]carbazole-based small molecule agonists of the thrombopoietin (Tpo) receptor.
    Bioorganic & medicinal chemistry letters (22 August 2008)
    by Phil B B Alper, Thomas H H Marsilje, Daniel Mutnick, Wenshuo Lu, Arnab Chatterjee, Michael J J Roberts, Yun He, Donald S S Karanewsky, Donald Chow, Jianmin Lao, Andrea Gerken, Tove Tuntland, Bo Liu, Jonathan Chang, Perry Gordon, H Martin Seidel, Shin-Shay S Tian
    posted to xf tpo sm ppi 2008 by higueruelo on 2008-09-12 14:06:58 as ***
  • Optimization of small molecule agonists of the thrombopoietin (Tpo) receptor derived from a benzo[a]carbazole hit scaffold.
    Bioorganic & medicinal chemistry letters (26 August 2008)
    by Thomas H H Marsilje, Phil B B Alper, Wenshuo Lu, Daniel Mutnick, Pierre-Yves Y Michellys, Yun He, Donald S S Karanewsky, Donald Chow, Andrea Gerken, Jianmin Lao, Min-Ju J Kim, H Martin M Seidel, Shin-Shay S Tian
    posted to xf tpo sm ppi 2008 by higueruelo on 2008-09-12 14:06:14 as ***
  • Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.
    Journal of medicinal chemistry, Vol. 44, No. 22. (25 October 2001), pp. 3730-3745.
    by KJ Duffy, MG Darcy, E Delorme, SB Dillon, DF Eppley, C Erickson-Miller, L Giampa, CB Hopson, Y Huang, RM Keenan, P Lamb, L Leong, N Liu, SG Miller, AT Price, J Rosen, R Shah, TN Shaw, H Smith, KC Stark, SS Tian, C Tyree, KJ Wiggall, L Zhang, JI Luengo
    posted to xf tpo sm ppi 2001 by higueruelo on 2008-09-12 14:03:10 as ***
  • Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics.
    Journal of medicinal chemistry, Vol. 45, No. 17. (15 August 2002), pp. 3573-3575.
    by KJ Duffy, AN Shaw, E Delorme, SB Dillon, C Erickson-Miller, L Giampa, Y Huang, RM Keenan, P Lamb, N Liu, SG Miller, AT Price, J Rosen, H Smith, KJ Wiggall, L Zhang, JI Luengo
    posted to xf tpo sm ppi 2002 by higueruelo on 2008-09-12 14:02:40 as ***
  • Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics.
    Journal of medicinal chemistry, Vol. 45, No. 17. (15 August 2002), pp. 3576-3578.
    by KJ Duffy, AT Price, E Delorme, SB Dillon, C Duquenne, C Erickson-Miller, L Giampa, Y Huang, RM Keenan, P Lamb, N Liu, SG Miller, J Rosen, AN Shaw, H Smith, KJ Wiggall, L Zhang, JI Luengo
    posted to xf tpo sm ppi 2002 by higueruelo on 2008-09-12 14:01:36 as ***
  • Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist.
    Experimental hematology, Vol. 33, No. 1. (January 2005), pp. 85-93.
    by CL Erickson-Miller, E DeLorme, SS Tian, CB Hopson, K Stark, L Giampa, EI Valoret, KJ Duffy, JL Luengo, J Rosen, SG Miller, SB Dillon, P Lamb
    posted to xf tpo sm ppi 2005 by higueruelo on 2008-09-12 14:00:49 as ***
  • Biologic aspects of thrombopoietin and the development of novel thrombopoietic agents for clinical use.
    Current drug discovery technologies, Vol. 4, No. 3. (October 2007), pp. 162-173.
    by ML Evangelista, S Amadori, R Stasi
    posted to xf tpo sm review ppi 2007 by higueruelo on 2008-09-12 14:00:07 as ***
  • Erythropoietin mimetics derived from solution phase combinatorial libraries.
    Journal of the American Chemical Society, Vol. 124, No. 4. (30 January 2002), pp. 544-555.
    by J Goldberg, Q Jin, Y Ambroise, S Satoh, J Desharnais, K Capps, DL Boger
    posted to xf sm ppi epo 2002 by higueruelo on 2008-09-12 11:22:04 as **
  • Towards erythropoietin mimicking small molecules.
    Bioorganic & medicinal chemistry letters, Vol. 17, No. 2. (15 January 2007), pp. 379-384.
    by A Dömling, B Beck, W Baumbach, G Larbig
    posted to xf sm ppi epo 2007 by higueruelo on 2008-09-12 11:21:30 as ***
  • Mimicry of erythropoietin by a nonpeptide molecule.
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 21. (12 October 1999), pp. 12156-12161.
    by SA Qureshi, RM Kim, Z Konteatis, DE Biazzo, H Motamedi, R Rodrigues, JA Boice, JR Calaycay, MA Bednarek, P Griffin, YD Gao, K Chapman, DF Mark
    posted to xf sm ppi epo 1999 by higueruelo on 2008-09-11 14:54:31 as ***
  • Inhibitors Targeting the LFA-1/ICAM-1 Cell-Adhesion Interaction: Design and Mechanism of Action.
    Current pharmaceutical design, Vol. 14, No. 22. (2008), pp. 2128-2139.
    by T Zimmerman, FJ Blanco
    posted to xf sm review ppi integrins 2008 by higueruelo on 2008-09-11 14:04:05 as ***
  • Small Molecule Inhibitors of the p53-MDM2.
    Current medicinal chemistry, Vol. 15, No. 17. (2008), pp. 1720-1730.
    by CQ Hu, YZ Hu
    posted to xf sm review ppi p53 mdm2 2008 by higueruelo on 2008-09-10 16:16:22 as ***
  • Small molecules targeting p53 to improve antitumor therapy.
    Mini reviews in medicinal chemistry, Vol. 8, No. 9. (August 2008), pp. 856-868.
    by GL Beretta, L Gatti, V Benedetti, P Perego, F Zunino
    posted to xf sm review ppi p53 2008 by higueruelo on 2008-09-05 12:20:01 as ***
  • Expanding circle of inhibition: small-molecule inhibitors of bcl-2 as anticancer cell and antiangiogenic agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 26, No. 25. (1 September 2008), pp. 4180-4188.
    by BD Zeitlin, IJ Zeitlin, JE Nör
    posted to xf sm ppi bcl2 2008 by higueruelo on 2008-09-04 16:19:59 as ***
  • Targeting the MDM2-p53 Interaction for Cancer Therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, No. 17. (1 September 2008), pp. 5318-5324.
    by S Shangary, S Wang
    posted to xf sm review ppi p53 mdm2 2008 by higueruelo on 2008-09-04 16:18:00 as ***
  • Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.
    Journal of cellular physiology (2 September 2008)
    by Asfar S S Azmi, Ramzi M M Mohammad
    posted to xf sm review ppi bcl2 2008 by higueruelo on 2008-09-04 16:16:42 as ***
  • Modulation of biomolecular interactions with complex-binding small molecules.
    Methods (San Diego, Calif.) (18 June 2008)
    by Zheng Cai, Mark I I Greene, Alan Berezov
    posted to xf sm ppi method denovo 2008 by higueruelo on 2008-09-03 17:19:28 as ***
  • High-throughput screening assays to discover small-molecule inhibitors of protein interactions.
    Current drug discovery technologies, Vol. 5, No. 3. (August 2008), pp. 190-199.
    by P Colas
    posted to xf sm review ppi method assays 2008 by higueruelo on 2008-09-03 17:17:27 as ***
  • Small-molecule inhibitors of protein-protein interactions.
    Current opinion in drug discovery & development, Vol. 11, No. 5. (September 2008), pp. 666-674.
    by T Berg
    posted to xf sm review ppi 2008 by higueruelo on 2008-09-03 17:10:46 as ***
  • Inhibition of transcription factors with small organic molecules.
    Current opinion in chemical biology (13 August 2008)
    by Thorsten Berg
    posted to 2008 ppi review sm tf xf by higueruelo on 2008-08-29 13:35:11 as *** along with 1 person zimbo1
  • Modulating G-Protein Coupled Receptor/G-Protein Signal Transduction by Small Molecules Suggested by Virtual Screening
    J. Med. Chem. (16 August 2008)
    by Christina M Taylor, Yaniv Barda, Oleg G Kisselev, Garland R Marshall
    posted to 2008 gpcr ppi sm xf by higueruelo on 2008-08-29 13:33:13 as *** along with 1 person zimbo1
  • A5, a New Small-Molecule Inhibitor of CD4 D1 Obtained from a Computer-Aided Screening Method, Contributes to the Inhibition of CD4+ T-cell Function
    J Biomol Screen, Vol. 12, No. 6. (1 September 2007), pp. 800-808.
    by He Xiao, Jian-Nan Feng, Zu-Yin Yu, Lei Zhang, Ming Yu, Xin-Hua He, Song Li, Bei-Fen Shen, Yan Li
    posted to 2007 cd4 ppi sm xf by higueruelo on 2008-07-18 11:26:30 as ***
  • Kinase packing defects as drug targets.
    Drug discovery today, Vol. 12, No. 21-22. (November 2007), pp. 917-923.
    by A Crespo, A Fernández
    posted to 2007 dehydrons kinases sm by higueruelo on 2008-07-17 11:52:03 as **
  • Small molecular weight protein-protein interaction antagonists--an insurmountable challenge?
    Current Opinion in Chemical Biology, Vol. 12, No. 3. (June 2008), pp. 281-291.
    by Alexander Dömling
    posted to 2008 mdm2 p53 ppi sm xf by higueruelo on 2008-07-17 10:06:39 as ***
  • The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1.
    Bioorganic & medicinal chemistry (18 June 2008)
    by Michael Prakesch, Alexey Yu Y Denisov, Marwen Naim, Kalle Gehring, Prabhat Arya
    posted to 2008 bclxl mcl1 ppi sm xf by higueruelo on 2008-07-14 14:46:54 as ***
  • A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally.
    The Journal of allergy and clinical immunology, Vol. 122, No. 1. (July 2008)
    by E Mazuc, BO Villoutreix, O Malbec, T Roumier, S Fleury, JP Leonetti, D Dombrowicz, M Daëron, P Martineau, P Dariavach
    posted to 2008 ppi sm syk xf by higueruelo on 2008-07-11 10:53:15 as ***
  • Recent Developments in Fragment-Based Drug Discovery
    Journal of Medicinal Chemistry, Vol. 51, No. 13. (2008), pp. 3661-3680.
    by Miles Congreve, Gianni Chessari, Dominic Tisi, Andrew J Woodhead
    posted to 2008 fragments ppi review sm xf by higueruelo on 2008-07-08 17:43:55 as ***
  • Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.
    Angewandte Chemie (International ed. in English), Vol. 43, No. 16. (13 April 2004), pp. 2109-2112.
    by R Fasan, RL Dias, K Moehle, O Zerbe, JW Vrijbloed, D Obrecht, JA Robinson
    posted to 2004 betaturn mdm2 p53 peptidomimetics sm xf by higueruelo on 2008-07-01 16:50:05 as ***
  • G Protein betagamma Subunits as Targets for Small Molecule Therapeutic Development.
    Combinatorial chemistry & high throughput screening, Vol. 11, No. 5. (June 2008), pp. 382-395.
    by AV Smrcka, DM Lehmann, AL Dessal
    posted to 2008 gbetagamma gpcr method ppi sm vs by higueruelo on 2008-07-01 16:20:22 as **
  • Screening for Antiviral Inhibitors of the HIV Integrase--LEDGF/p75 Interaction Using the AlphaScreenTM Luminescent Proximity Assay
    J Biomol Screen, Vol. 13, No. 5. (1 June 2008), pp. 406-414.
    by Yan Hou, Debra E Mcguinness, Andrew J Prongay, Boris Feld, Paul Ingravallo, Robert A Ogert, Charles A Lunn, John A Howe
    posted to 2008 hiv1 method ppi sm xf by higueruelo on 2008-07-01 11:26:23 as ***
  • Web Server To Identify Similarity of Amino Acid Motifs to Compounds (SAAMCO)
    J. Chem. Inf. Model. (21 June 2008)
    by Fergal P Casey, Norman E Davey, Ivan Baran, Radka S Varekova, Denis C Shields
    posted to 2008 peptidomimetics ppi sm by higueruelo on 2008-06-27 17:08:21 as **
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