Attractor reliability reveals deterministic structure in neuronal spike trains.

@article{citeulike:2972443, abstract = {When periodic current is injected into an integrate-and-fire model neuron, the voltage as a function of time converges from different initial conditions to an attractor that produces reproducible sequences of spikes. The attractor reliability is a measure of the stability of spike trains against intrinsic noise and is quantified here as the inverse of the number of distinct spike trains obtained in response to repeated presentations of the same stimulus. High reliability characterizes neurons that can support a spike-time code, unlike neurons with discharges forming a renewal process (such as a Poisson process). These two classes of responses cannot be distinguished using measures based on the spike-time histogram, but they can be identified by the attractor dynamics of spike trains, as shown here using a new method for calculating the attractor reliability. We applied these methods to spike trains obtained from current injection into cortical neurons recorded in vitro. These spike trains did not form a renewal process and had a higher reliability compared to renewal-like processes with the same spike-time histogram.}, address = {Sloan-Swartz Center for Theoretical Neurobiology and Computational Neurobiology Lab, Salk Institute, La Jolla, CA 92037, USA. tiesinga@salk.edu}, author = {Tiesinga, P. H. and Fellous, J. M. and Sejnowski, T. J. }, citeulike-article-id = {2972443}, doi = {http://dx.doi.org/10.1162/08997660260028647}, issn = {0899-7667}, journal = {Neural computation}, keywords = {neuronal\_dynamics, reliability, single\_neuron, temporal\_coding}, month = {July}, number = {7}, pages = {1629--1650}, posted-at = {2008-07-08 12:46:30}, priority = {2}, title = {Attractor reliability reveals deterministic structure in neuronal spike trains.}, url = {http://dx.doi.org/10.1162/08997660260028647}, volume = {14}, year = {2002} }

TY - JOUR ID - citeulike:2972443 L3 - citeulike-article-id:2972443 TI - Attractor reliability reveals deterministic structure in neuronal spike trains. JF - Neural computation VL - 14 IS - 7 SP - 1629 EP - 1650 AD - Sloan-Swartz Center for Theoretical Neurobiology and Computational Neurobiology Lab, Salk Institute, La Jolla, CA 92037, USA. tiesinga@salk.edu SN - 0899-7667 N2 - When periodic current is injected into an integrate-and-fire model neuron, the voltage as a function of time converges from different initial conditions to an attractor that produces reproducible sequences of spikes. The attractor reliability is a measure of the stability of spike trains against intrinsic noise and is quantified here as the inverse of the number of distinct spike trains obtained in response to repeated presentations of the same stimulus. High reliability characterizes neurons that can support a spike-time code, unlike neurons with discharges forming a renewal process (such as a Poisson process). These two classes of responses cannot be distinguished using measures based on the spike-time histogram, but they can be identified by the attractor dynamics of spike trains, as shown here using a new method for calculating the attractor reliability. We applied these methods to spike trains obtained from current injection into cortical neurons recorded in vitro. These spike trains did not form a renewal process and had a higher reliability compared to renewal-like processes with the same spike-time histogram. KW - neuronal_dynamics KW - reliability KW - single_neuron KW - temporal_coding AU - Tiesinga, PH AU - Fellous, JM AU - Sejnowski, TJ PY - 2002/07// UR - http://dx.doi.org/10.1162/08997660260028647 ER -