A comparative analysis of kinetic models of erythrocyte glycolysis

by: FB du Preez, R Conradie, GP Penkler, K Holm, FLJ van Dooren, JL Snoep

Journal of Theoretical Biology, Vol. In Press, Corrected Proof

View FullText article

DOI, Pubmed, Hubmed, ScienceDirect

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

westoll, dullhunk

Find related articles with these CiteULike tags

erythrocyte, glycolysis, jacky-snoep, kinetic-model

Abstract

Since the 1970s, with Heinrich as a pioneer in the field, numerous kinetic models of erythrocyte glycolysis have been constructed. A functional comparison of eight of these models indicates that the production of ATP and GSH in the red blood cell is largely controlled by the demand reactions. The rate characteristics for the supply and demand blocks indicate a good homeostatic control of ATP and GSH concentrations at different work loads for the pathway, while the production rates of ATP and GSH can be adjusted as needed by the demand reactions.

@article{citeulike:2089054, abstract = {Since the 1970s, with Heinrich as a pioneer in the field, numerous kinetic models of erythrocyte glycolysis have been constructed. A functional comparison of eight of these models indicates that the production of ATP and GSH in the red blood cell is largely controlled by the demand reactions. The rate characteristics for the supply and demand blocks indicate a good homeostatic control of ATP and GSH concentrations at different work loads for the pathway, while the production rates of ATP and GSH can be adjusted as needed by the demand reactions.}, author = {du Preez, F. B. and Conradie, R. and Penkler, G. P. and Holm, K. and van Dooren, F. L. J. and Snoep, J. L. }, citeulike-article-id = {2089054}, doi = {http://dx.doi.org/10.1016/j.jtbi.2007.10.006}, journal = {Journal of Theoretical Biology}, keywords = {jacky-snoep}, posted-at = {2008-06-26 12:19:25}, priority = {2}, title = {A comparative analysis of kinetic models of erythrocyte glycolysis}, url = {http://dx.doi.org/10.1016/j.jtbi.2007.10.006}, volume = {In Press, Corrected Proof} }

RIS record

TY - JOUR ID - citeulike:2089054 L3 - citeulike-article-id:2089054 TI - A comparative analysis of kinetic models of erythrocyte glycolysis JF - Journal of Theoretical Biology VL - In Press, Corrected Proof N2 - Since the 1970s, with Heinrich as a pioneer in the field, numerous kinetic models of erythrocyte glycolysis have been constructed. A functional comparison of eight of these models indicates that the production of ATP and GSH in the red blood cell is largely controlled by the demand reactions. The rate characteristics for the supply and demand blocks indicate a good homeostatic control of ATP and GSH concentrations at different work loads for the pathway, while the production rates of ATP and GSH can be adjusted as needed by the demand reactions. KW - jacky-snoep AU - du Preez, FB AU - Conradie, R AU - Penkler, GP AU - Holm, K AU - van Dooren, FLJ AU - Snoep, JL UR - http://dx.doi.org/10.1016/j.jtbi.2007.10.006 ER -

RIS BibTeX