Delta-notch lateral inhibitory patterning in the emergence of ciliated cells in Xenopus: experimental observations and a gene network model

by: G Marnellos, G Deblandre, E Mjolsness, C Kintner

(2000), pp. 326-337.

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Abstract

this paper we examine lateral inhibition during the emergence of ciliated cells in Xenopus embryonic skin, using experimental manipulations of the Delta-Notch pathway and a connectionist gene-network model of the process. The results of our model are in agreement with previous models of regular patterning through lateral inhibition and reproduce the observations of our experimental assays. Moreover, the model provides an account for the variability of embryonic responses to the experimental...

@inproceedings{citeulike:3038780, abstract = {this paper we examine lateral inhibition during the emergence of ciliated cells in Xenopus embryonic skin, using experimental manipulations of the Delta-Notch pathway and a connectionist gene-network model of the process. The results of our model are in agreement with previous models of regular patterning through lateral inhibition and reproduce the observations of our experimental assays. Moreover, the model provides an account for the variability of embryonic responses to the experimental...}, author = {Marnellos, G. and Deblandre, G. and Mjolsness, E. and Kintner, C. }, booktitle = {Pacific Symposium on Biocomputing}, citeulike-article-id = {3038780}, keywords = {indirect}, pages = {326--337}, posted-at = {2008-07-24 10:17:46}, priority = {2}, title = {Delta-notch lateral inhibitory patterning in the emergence of ciliated cells in Xenopus: experimental observations and a gene network model}, url = {http://citeseer.ist.psu.edu/237228.html}, year = {2000} }

RIS record

TY - CONF ID - citeulike:3038780 L3 - citeulike-article-id:3038780 TI - Delta-notch lateral inhibitory patterning in the emergence of ciliated cells in Xenopus: experimental observations and a gene network model T2 - Pacific Symposium on Biocomputing SP - 326 EP - 337 N2 - this paper we examine lateral inhibition during the emergence of ciliated cells in Xenopus embryonic skin, using experimental manipulations of the Delta-Notch pathway and a connectionist gene-network model of the process. The results of our model are in agreement with previous models of regular patterning through lateral inhibition and reproduce the observations of our experimental assays. Moreover, the model provides an account for the variability of embryonic responses to the experimental... KW - indirect AU - Marnellos, G AU - Deblandre, G AU - Mjolsness, E AU - Kintner, C PY - 2000/// UR - http://citeseer.ist.psu.edu/237228.html ER -

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