When gene marriages don't work out: divorce by subfunctionalization.

@article{citeulike:2988289, abstract = {We describe how a bifunctional gene, encoding two proteins by alternative splicing, arose when the chloroplast gene RPL32 integrated into an intron of the nuclear gene SODcp in an ancestor of mangrove and poplar trees. Mangrove retains the alternatively spliced chimeric gene, but in poplar it underwent duplication and complete subfunctionalization, through complementary structural degeneration, to re-form separate RPL32 and SODcp genes.}, address = {Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.}, author = {Cusack, B. P. and Wolfe, K. H. }, citeulike-article-id = {2988289}, doi = {http://dx.doi.org/10.1016/j.tig.2007.03.010}, issn = {0168-9525}, journal = {Trends in genetics : TIG}, keywords = {duplication, subfunctionalisation}, month = {June}, number = {6}, pages = {270--272}, posted-at = {2008-07-11 14:35:19}, priority = {2}, title = {When gene marriages don't work out: divorce by subfunctionalization.}, url = {http://dx.doi.org/10.1016/j.tig.2007.03.010}, volume = {23}, year = {2007} }

TY - JOUR ID - citeulike:2988289 L3 - citeulike-article-id:2988289 TI - When gene marriages don't work out: divorce by subfunctionalization. JF - Trends in genetics : TIG VL - 23 IS - 6 SP - 270 EP - 272 AD - Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland. SN - 0168-9525 N2 - We describe how a bifunctional gene, encoding two proteins by alternative splicing, arose when the chloroplast gene RPL32 integrated into an intron of the nuclear gene SODcp in an ancestor of mangrove and poplar trees. Mangrove retains the alternatively spliced chimeric gene, but in poplar it underwent duplication and complete subfunctionalization, through complementary structural degeneration, to re-form separate RPL32 and SODcp genes. KW - duplication KW - subfunctionalisation AU - Cusack, BP AU - Wolfe, KH PY - 2007/06// UR - http://dx.doi.org/10.1016/j.tig.2007.03.010 ER -