Analysis of protein interactions using fluorescence technologies

@article{citeulike:2425883, abstract = {Biophotonics techniques, especially those involving fluorescence, are widely used in proteomics to characterize the in vitro interactions between proteins in high-throughput mode. On the other hand, fluorescence-based imaging studies often show that protein activity is regulated through large protein complexes that transiently form at specific sites in the cell. One could therefore argue that a systematic functional analysis of the human proteome requires technologies that are capable of time and spatially resolved, multiplexed analysis of protein interactions within cells.}, author = {Yan, Yuling and Marriott, Gerard }, citeulike-article-id = {2425883}, doi = {http://dx.doi.org/10.1016/j.cbpa.2003.08.017}, journal = {Current Opinion in Chemical Biology}, month = {October}, number = {5}, pages = {635--640}, posted-at = {2008-02-25 15:51:08}, priority = {0}, title = {Analysis of protein interactions using fluorescence technologies}, url = {http://dx.doi.org/10.1016/j.cbpa.2003.08.017}, volume = {7}, year = {2003} }

TY - JOUR ID - citeulike:2425883 L3 - citeulike-article-id:2425883 TI - Analysis of protein interactions using fluorescence technologies JF - Current Opinion in Chemical Biology VL - 7 IS - 5 SP - 635 EP - 640 N2 - Biophotonics techniques, especially those involving fluorescence, are widely used in proteomics to characterize the in vitro interactions between proteins in high-throughput mode. On the other hand, fluorescence-based imaging studies often show that protein activity is regulated through large protein complexes that transiently form at specific sites in the cell. One could therefore argue that a systematic functional analysis of the human proteome requires technologies that are capable of time and spatially resolved, multiplexed analysis of protein interactions within cells. AU - Yan, Yuling AU - Marriott, Gerard PY - 2003/10// UR - http://dx.doi.org/10.1016/j.cbpa.2003.08.017 ER -