MRI findings in boys with specific language impairment.

@article{citeulike:3115939, abstract = {Magnetic resonance imaging scans of specifically language-impaired (SLI) boys were examined to determine whether atypical cerebral findings could be documented in children whose primary deficits were in language skills. Clinical examination of the scans failed to reveal any visually obvious lesions or abnormalities. In contrast, measurement of the scans revealed atypical perisylvian asymmetries in most of these subjects. The distribution of perisylvian asymmetries in SLI subjects was significantly different from the distribution in controls (p less than .01). Measurement of other brain regions revealed that extraperisylvian areas were occasionally deviant in individual SLI subjects; but no one region was consistently deviant across the SLI group. Thus, only atypical perisylvian asymmetries were linked to the language disorder. These neuroanatomical findings suggest that a prenatal alteration of brain development underlies specific language impairment.}, address = {Child Language Laboratory, University of Arizona, Tucson 85702.}, author = {Plante, E. and Swisher, L. and Vance, R. and Rapcsak, S. }, citeulike-article-id = {3115939}, issn = {0093-934X}, journal = {Brain and language}, keywords = {brain, cortex, mri, prenatal-development, sli, sli-project}, month = {July}, number = {1}, pages = {52--66}, posted-at = {2008-08-13 18:27:33}, priority = {3}, title = {MRI findings in boys with specific language impairment.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/1884191}, volume = {41}, year = {1991} }

TY - JOUR ID - citeulike:3115939 L3 - citeulike-article-id:3115939 N2 - Magnetic resonance imaging scans of specifically language-impaired (SLI) boys were examined to determine whether atypical cerebral findings could be documented in children whose primary deficits were in language skills. Clinical examination of the scans failed to reveal any visually obvious lesions or abnormalities. In contrast, measurement of the scans revealed atypical perisylvian asymmetries in most of these subjects. The distribution of perisylvian asymmetries in SLI subjects was significantly different from the distribution in controls (p less than .01). Measurement of other brain regions revealed that extraperisylvian areas were occasionally deviant in individual SLI subjects; but no one region was consistently deviant across the SLI group. Thus, only atypical perisylvian asymmetries were linked to the language disorder. These neuroanatomical findings suggest that a prenatal alteration of brain development underlies specific language impairment. IS - 1 JF - Brain and language SN - 0093-934X AD - Child Language Laboratory, University of Arizona, Tucson 85702. EP - 66 TI - MRI findings in boys with specific language impairment. VL - 41 SP - 52 KW - brain KW - cortex KW - mri KW - prenatal-development KW - sli KW - sli-project AU - Plante, E AU - Swisher, L AU - Vance, R AU - Rapcsak, S PY - 1991/07// UR - http://view.ncbi.nlm.nih.gov/pubmed/1884191 ER -