Neural correlates of perceptual filling-in of an artificial scotoma in humans.

@article{citeulike:1206272, abstract = {When a uniformly illuminated surface is placed eccentrically on a dynamic textured background, after a few seconds, it is perceived to disappear and be replaced by the background texture. Such texture filling-in is thought to occur in retinotopic visual cortex, but it has proven difficult to distinguish the contributions of invisible target and visible background to signals measured in these areas. Here, we used magnetoencephalography to measure time-dependent brain responses in human observers experiencing texture completion. We measured responses specifically associated with the filled-in target, by isolating neural population signals entrained at the frequency of flicker of the target. When perceptual completion occurred, and the target became invisible, there was significant reduction in the magnetoencephalography power at the target frequency over contralateral posterior sensors. However, even a subjectively invisible target nevertheless evoked frequency-specific signals compared with a no-target baseline. These data represent evidence for a persistent target-specific representation even for stimuli rendered invisible because of perceptual filling-in.}, address = {*Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom.}, author = {Weil, R. S. and Kilner, J. M. and Haynes, J. D. and Rees, G. }, citeulike-article-id = {1206272}, doi = {http://dx.doi.org/10.1073/pnas.0609294104}, issn = {0027-8424}, journal = {Proc Natl Acad Sci U S A}, keywords = {jc-pnas}, month = {March}, number = {12}, pages = {5211--5216}, posted-at = {2007-04-04 16:43:20}, priority = {2}, title = {Neural correlates of perceptual filling-in of an artificial scotoma in humans.}, url = {http://dx.doi.org/10.1073/pnas.0609294104}, volume = {104}, year = {2007} }

TY - JOUR ID - citeulike:1206272 L3 - citeulike-article-id:1206272 TI - Neural correlates of perceptual filling-in of an artificial scotoma in humans. JF - Proc Natl Acad Sci U S A VL - 104 IS - 12 SP - 5211 EP - 5216 AD - *Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom. SN - 0027-8424 N2 - When a uniformly illuminated surface is placed eccentrically on a dynamic textured background, after a few seconds, it is perceived to disappear and be replaced by the background texture. Such texture filling-in is thought to occur in retinotopic visual cortex, but it has proven difficult to distinguish the contributions of invisible target and visible background to signals measured in these areas. Here, we used magnetoencephalography to measure time-dependent brain responses in human observers experiencing texture completion. We measured responses specifically associated with the filled-in target, by isolating neural population signals entrained at the frequency of flicker of the target. When perceptual completion occurred, and the target became invisible, there was significant reduction in the magnetoencephalography power at the target frequency over contralateral posterior sensors. However, even a subjectively invisible target nevertheless evoked frequency-specific signals compared with a no-target baseline. These data represent evidence for a persistent target-specific representation even for stimuli rendered invisible because of perceptual filling-in. KW - jc-pnas AU - Weil, RS AU - Kilner, JM AU - Haynes, JD AU - Rees, G PY - 2007/03/20/ UR - http://dx.doi.org/10.1073/pnas.0609294104 ER -