Intracerebral P3-like waveforms and the length of the stimulus-response interval in a visual oddball paradigm

@article{citeulike:278243, abstract = {ObjectiveThis study investigated the possible linkage of intracerebrally recorded P3-like waveforms to the processes induced by stimulus perception or motor response formation.MethodsEvent-related potentials were recorded from 560 cerebral sites in 17 patients suffering from intractable epilepsy during visual oddball task. Potentials evoked by the target stimuli were sorted according to button-pressing response times, and the P3 waveform was analyzed both in stimulus-locked and response-locked averages, which were separately averaged for fast and slow responses.ResultsP3-like waveforms were identified in 180 sites in 17 patients. Three different types of P3-like waveforms, diffusely distributed within the brain, were found: (1) time-locked to the stimulus (30 sites in 11 patients); (2) time-locked to the motor response (52 sites in 13 patients); and (3) with ambiguous time relationship to stimulus and motor response (98 sites in 16 patients).ConclusionsThe intracerebral P3-like waveform could represent different processes involved in performing active oddball tasks. Therefore, our results support the hypothesis that the P3 waveform registered by surface electrodes could be a heterogeneous phenomenon.SignificanceThese results provide evidence that the P3 waveform is not only related to stimulus processing, which differs from what has been generally claimed in the literature.}, author = {Roman, Robert and Brazdil, Milan and Jurak, Pavel and Rektor, Ivan and Kukleta, Miloslav }, citeulike-article-id = {278243}, doi = {10.1016/j.clinph.2004.07.016}, journal = {Clinical Neurophysiology}, keywords = {cksearch, erps, oddball, p300}, month = {}, number = {1}, pages = {160--171}, posted-at = {2005-08-10 23:51:52}, priority = {2}, title = {Intracerebral P3-like waveforms and the length of the stimulus-response interval in a visual oddball paradigm}, url = {http://dx.doi.org/10.1016/j.clinph.2004.07.016}, volume = {116}, year = {2005} }

TY - JOUR ID - citeulike:278243 L3 - citeulike-article-id:278243 TI - Intracerebral P3-like waveforms and the length of the stimulus-response interval in a visual oddball paradigm JF - Clinical Neurophysiology VL - 116 IS - 1 SP - 160 EP - 171 N2 - ObjectiveThis study investigated the possible linkage of intracerebrally recorded P3-like waveforms to the processes induced by stimulus perception or motor response formation.MethodsEvent-related potentials were recorded from 560 cerebral sites in 17 patients suffering from intractable epilepsy during visual oddball task. Potentials evoked by the target stimuli were sorted according to button-pressing response times, and the P3 waveform was analyzed both in stimulus-locked and response-locked averages, which were separately averaged for fast and slow responses.ResultsP3-like waveforms were identified in 180 sites in 17 patients. Three different types of P3-like waveforms, diffusely distributed within the brain, were found: (1) time-locked to the stimulus (30 sites in 11 patients); (2) time-locked to the motor response (52 sites in 13 patients); and (3) with ambiguous time relationship to stimulus and motor response (98 sites in 16 patients).ConclusionsThe intracerebral P3-like waveform could represent different processes involved in performing active oddball tasks. Therefore, our results support the hypothesis that the P3 waveform registered by surface electrodes could be a heterogeneous phenomenon.SignificanceThese results provide evidence that the P3 waveform is not only related to stimulus processing, which differs from what has been generally claimed in the literature. KW - cksearch KW - erps KW - oddball KW - p300 AU - Roman, Robert AU - Brazdil, Milan AU - Jurak, Pavel AU - Rektor, Ivan AU - Kukleta, Miloslav PY - 2005/0// UR - http://dx.doi.org/10.1016/j.clinph.2004.07.016 ER -