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A_Coletta_Thesis camptothecin [34 articles]

最近 A_Coletta_Thesis さんのライブラリに追加された論文の中から タグ camptothecin. You can also see everyone's camptothecin.
  • Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex.
    Journal of medicinal chemistry, Vol. 48, No. 7. (7 April 2005), pp. 2336-2345.
    by BL Staker, MD Feese, M Cushman, Y Pommier, D Zembower, L Stewart, AB Burgin
    posted to camptothecin topoisomerase topotecan by A_Coletta_Thesis on 2008-07-08 11:26:54 as **
  • Topoisomerase I inhibitors: camptothecins and beyond
    Nature Reviews Cancer, Vol. 6, No. 10., pp. 789-802.
    by Yves Pommier
    posted to camptothecin irinotecan topoisomerase topotecan by A_Coletta_Thesis on 2008-07-08 10:22:54 as ** along with 1 person moonycinzia
  • The dihydropyridine dexniguldipine hydrochloride inhibits cleavage and religation reactions of eukaryotic DNA topoisomerase I.
    Biochemistry, Vol. 36, No. 35. (2 September 1997), pp. 10777-10783.
    by T Straub, C Boesenberg, V Gekeler, F Boege
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 23:29:08 as **
  • Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.
    Journal of medicinal chemistry, Vol. 34, No. 1. (January 1991), pp. 98-107.
    by WD Kingsbury, JC Boehm, DR Jakas, KG Holden, SM Hecht, G Gallagher, MJ Caranfa, FL McCabe, LF Faucette, RK Johnson
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 22:08:26 as **
  • Expression of human topoisomerase I with a partial deletion of the linker region yields monomeric and dimeric enzymes that respond differently to camptothecin.
    The Journal of biological chemistry, Vol. 275, No. 33. (18 August 2000), pp. 25820-25830.
    by GC Ireton, L Stewart, LH Parker, JJ Champoux
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 22:06:28 as **
  • Structure-based analysis of the effects of camptothecin on the activities of human topoisomerase I.
    Annals of the New York Academy of Sciences, Vol. 922 (2000), pp. 56-64.
    by JJ Champoux
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 22:04:30 as **
  • Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line.
    Biochemical and biophysical research communications, Vol. 188, No. 2. (30 October 1992), pp. 571-577.
    by N Kubota, F Kanzawa, K Nishio, Y Takeda, T Ohmori, Y Fujiwara, Y Terashima, N Saijo
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 22:00:52 as **
  • Topoisomerase I alteration in a camptothecin-resistant cell line derived from Chinese hamster DC3F cells in culture.
    Cancer research, Vol. 52, No. 7. (1 April 1992), pp. 1848-1854.
    by A Tanizawa, Y Pommier
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:57:03 as **
  • Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line.
    Cancer research, Vol. 61, No. 5. (1 March 2001), pp. 1964-1969.
    by Y Urasaki, GS Laco, P Pourquier, Y Takebayashi, G Kohlhagen, C Gioffre, H Zhang, D Chatterjee, P Pantazis, Y Pommier
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:55:32 as **
  • Effects of mutations in the F361 to R364 region of topoisomerase I (Topo I), in the presence and absence of 9-aminocamptothecin, on the Topo I-DNA interaction.
    Anti-cancer drugs, Vol. 10, No. 7. (August 1999), pp. 647-653.
    by CD Pond, XG Li, EH Rubin, LR Barrows
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:50:42 as **
  • Identification of mutations at DNA topoisomerase I responsible for camptothecin resistance.
    Cancer research, Vol. 57, No. 8. (15 April 1997), pp. 1516-1522.
    by LF Wang, CY Ting, CK Lo, JS Su, LA Mickley, AT Fojo, J Whang-Peng, J Hwang
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:49:14 as **
  • Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine.
    Cancer research, Vol. 53, No. 18. (15 September 1993), pp. 4343-4348.
    by P Benedetti, P Fiorani, L Capuani, JC Wang
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:33:06 as ** along with 1 person moonycinzia
  • Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites.
    Nucleic acids research, Vol. 19, No. 1. (11 January 1991), pp. 69-75.
    by H Tamura, C Kohchi, R Yamada, T Ikeda, O Koiwai, E Patterson, JD Keene, K Okada, E Kjeldsen, K Nishikawa
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:31:43 as **
  • An ab initio quantum mechanics calculation that correlates with ligand orientation and DNA cleavage site selectivity in camptothecin-DNA-topoisomerase I ternary cleavage complexes.
    Journal of the American Chemical Society, Vol. 127, No. 28. (20 July 2005), pp. 9960-9961.
    by X Xiao, M Cushman
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:24:34 as **
  • Effect of E-ring modifications in camptothecin on topoisomerase I inhibition: a quantum mechanics treatment.
    The Journal of organic chemistry, Vol. 70, No. 23. (11 November 2005), pp. 9584-9587.
    by X Xiao, M Cushman
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:24:16 as **
  • Sequence specificity of DNA topoisomerase I in the presence and absence of camptothecin.
    The EMBO journal, Vol. 6, No. 6. (June 1987), pp. 1817-1823.
    by B Thomsen, S Mollerup, BJ Bonven, R Frank, H Blöcker, OF Nielsen, O Westergaard
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:22:14 as **
  • On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex.
    Biochemistry, Vol. 28, No. 11. (30 May 1989), pp. 4629-4638.
    by RP Hertzberg, MJ Caranfa, SM Hecht
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:20:48 as **
  • Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, No. 19. (12 September 1995), pp. 8861-8865.
    by Y Pommier, G Kohlhagen, KW Kohn, F Leteurtre, MC Wani, ME Wall
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:16:39 as **
  • Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site.
    The Journal of biological chemistry, Vol. 265, No. 31. (5 November 1990), pp. 19287-19295.
    by RP Hertzberg, RW Busby, MJ Caranfa, KG Holden, RK Johnson, SM Hecht, WD Kingsbury
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:15:04 as **
  • New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site.
    Journal of molecular biology, Vol. 222, No. 3. (5 December 1991), pp. 669-678.
    by JQ Svejstrup, K Christiansen, II Gromova, AH Andersen, O Westergaard
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 21:09:50 as **
  • Irinotecan (Campto) in the treatment of pancreatic cancer.
    Expert review of anticancer therapy, Vol. 3, No. 5. (October 2003), pp. 587-593.
    by JF Pizzolato, LB Saltz
    posted to camptothecin irinotecan by A_Coletta_Thesis on 2008-07-07 18:56:21 as **
  • The camptothecins.
    Lancet, Vol. 361, No. 9376. (28 June 2003), pp. 2235-2242.
    by JF Pizzolato, LB Saltz
    posted to camptothecin by A_Coletta_Thesis on 2008-07-07 18:55:17 as **
  • A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues.
    Journal of pharmaceutical sciences, Vol. 81, No. 7. (July 1992), pp. 676-684.
    by J Fassberg, VJ Stella
    posted to camptothecin by A_Coletta_Thesis on 2008-07-07 18:52:51 as **
  • Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins.
    Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, No. 3. (March 2002), pp. 641-661.
    by R Garcia-Carbonero, JG Supko
    posted to camptothecin by A_Coletta_Thesis on 2008-07-07 18:50:18 as **
  • Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata
    J. Am. Chem. Soc., Vol. 88, No. 16. (20 August 1966), pp. 3888-3890.
    by ME Wall, MC Wani, CE Cook, KH Palmer, AT Mcphail, GA Sim
    posted to camptothecin by A_Coletta_Thesis on 2008-07-07 18:48:39 as **
  • Camptothecins: a review of their chemotherapeutic potential.
    Drugs, Vol. 62, No. 14. (2002), pp. 2039-2057.
    by H Ulukan, PW Swaan
    posted to camptothecin topotecan by A_Coletta_Thesis on 2008-07-07 18:38:09 as **
  • Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
    The Journal of biological chemistry, Vol. 278, No. 44. (31 October 2003), pp. 43268-43275.
    by P Fiorani, A Bruselles, M Falconi, G Chillemi, A Desideri, P Benedetti
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 18:00:41 as ** along with 1 person moonycinzia
  • Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin.
    Journal of medicinal chemistry, Vol. 41, No. 13. (18 June 1998), pp. 2216-2226.
    by Y Fan, JN Weinstein, KW Kohn, LM Shi, Y Pommier
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-07 16:29:06 as **
  • The mechanism of topoisomerase I poisoning by a camptothecin analog.
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 24. (26 November 2002), pp. 15387-15392.
    by BL Staker, K Hjerrild, MD Feese, CA Behnke, AB Burgin, L Stewart
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-05 14:53:24 as **
  • Mechanisms of camptothecin resistance by human topoisomerase I mutations.
    Journal of molecular biology, Vol. 339, No. 4. (11 June 2004), pp. 773-784.
    by JE Chrencik, BL Staker, AB Burgin, P Pourquier, Y Pommier, L Stewart, MR Redinbo
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-07-05 14:50:24 as **
  • New hints on the Ph-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach.
    J Am Chem Soc, Vol. 127, No. 44. (9 November 2005), pp. 15429-15436.
    by N Sanna, G Chillemi, A Grandi, S Castelli, A Desideri, V Barone
    posted to camptothecin topotecan by A_Coletta_Thesis on 2008-07-03 17:31:17 as ** along with 1 person AndreaColetta
  • Spectroscopic and Biochemical Characterisation of Self-Aggregates Formed by Antitumor Drugs of the Camptothecin Family: Their Possible Role In the Unique Mode of Drug Action
    Biochemical Pharmacology, Vol. 55, No. 8. (15 April 1998), pp. 1163-1174.
    by Igor Nabiev, Fabrice Fleury, Irina Kudelina, Yves Pommier, Françoise Charton, Jean-François Riou, Alain J Alix, Michel Manfait
    posted to camptothecin topoisomerase topotecan by A_Coletta_Thesis on 2008-06-12 15:47:49 as **
  • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    J. Biol. Chem., Vol. 260, No. 27. (25 November 1985), pp. 14873-14878.
    by Yh Hsiang, R Hertzberg, S Hecht, Lf Liu
    posted to camptothecin by A_Coletta_Thesis on 2008-06-12 11:43:19 as ** along with 1 person and 1 group cherrie CAOS
  • DNA topoisomerase-targeting antitumor drugs can be studied in yeast.
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, No. 20. (October 1988), pp. 7501-7505.
    by J Nitiss, JC Wang
    posted to camptothecin topoisomerase by A_Coletta_Thesis on 2008-06-12 11:09:43 as **
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