Introduction to NF-kappaB: players, pathways, perspectives.

by: TD Gilmore

Oncogene, Vol. 25, No. 51. (30 October 2006), pp. 6680-6684.

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Abstract

This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-kappaB family of transcription factors. NF-kappaB signaling is primarily regulated by inhibitor kappaB (IkappaB) proteins and the IkappaB kinase complex through two major pathways: the canonical and non-canonical NF-kappaB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-kappaB.

@article{citeulike:2145180, abstract = {This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-kappaB family of transcription factors. NF-kappaB signaling is primarily regulated by inhibitor kappaB (IkappaB) proteins and the IkappaB kinase complex through two major pathways: the canonical and non-canonical NF-kappaB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-kappaB.}, address = {Biology Department, Boston University, Boston, MA 02215, USA. gilmore@bu.edu}, author = {Gilmore, T. D. }, citeulike-article-id = {2145180}, doi = {10.1038/sj.onc.1209954}, issn = {0950-9232}, journal = {Oncogene}, month = {October}, number = {51}, pages = {6680--6684}, posted-at = {2007-12-19 11:58:22}, priority = {2}, title = {Introduction to NF-kappaB: players, pathways, perspectives.}, url = {http://dx.doi.org/10.1038/sj.onc.1209954}, volume = {25}, year = {2006} }

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TY - JOUR ID - citeulike:2145180 L3 - citeulike-article-id:2145180 TI - Introduction to NF-kappaB: players, pathways, perspectives. JF - Oncogene VL - 25 IS - 51 SP - 6680 EP - 6684 AD - Biology Department, Boston University, Boston, MA 02215, USA. gilmore@bu.edu SN - 0950-9232 N2 - This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-kappaB family of transcription factors. NF-kappaB signaling is primarily regulated by inhibitor kappaB (IkappaB) proteins and the IkappaB kinase complex through two major pathways: the canonical and non-canonical NF-kappaB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-kappaB. AU - Gilmore, TD PY - 2006/10/30/ UR - http://dx.doi.org/10.1038/sj.onc.1209954 ER -

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