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タグ: thrombin [39 articles]

Recent papers classified by the tag thrombin.
  • K+/Na+ Selectivity in K Channels and Valinomycin: Over-coordination Versus Cavity-size constraints
    Journal of Molecular Biology, Vol. 376, No. 1. (8 February 2008), pp. 13-22.
    by Sameer Varma, Dubravko Sabo, Susan B Rempe
    posted to biomembranes ion_channels solvation thrombin by sobolevnrm on 2008-03-10 11:41:18 as read along with 1 group baker-group
  • Ab Initio QM/MM Dynamics Simulation of the Tetrahedral Intermediate of Serine Proteases: Insights into the Active Site Hydrogen-Bonding Network
    J. Am. Chem. Soc., Vol. 124, No. 49. (11 December 2002), pp. 14780-14788.
    by M Topf, P Varnai, WG Richards
    posted to thrombin quantum_mechanics by sobolevnrm on 2008-05-27 17:34:05 as read along with 1 group baker-group
  • Analysis of Catalytic Mechanism of Serine Proteases. Viability of the Ring-Flip Hypothesis
    J. Phys. Chem. B (8 May 2008)
    by Steve Scheiner
    posted to thrombin by sobolevnrm on 2008-05-27 17:32:25 as read along with 1 group baker-group
  • Dynamics of single-file water chains inside nanoscale channels: physics, biological significance and applications
    Journal of Physics D: Applied Physics, Vol. 41, No. 10. (2008), 103002.
    by Haiping Fang, Rongzheng Wan, Xiaojing Gong, Hangjun Lu, Songyan Li
    posted to thrombin solvation nanotech by sobolevnrm on 2008-04-23 11:01:51 as read along with 1 group baker-group
  • Unusual 1H NMR chemical shifts support (His) Cepsilon 1---Hmiddle dotmiddle dotmiddle dotO==C H-bond: Proposal for reaction-driven ring flip mechanism in serine protease catalysis
    Proceedings of the National Academy of Sciences, Vol. 97, No. 19. (12 September 2000), pp. 10371-10376.
    by Elissa L Ash, James L Sudmeier, Regina M Day, Matthew Vincent, Ekaterina V Torchilin, Kristin C Haddad, Elizabeth M Bradshaw, David G Sanford, William W Bachovchin
    posted to thrombin kinetics by sobolevnrm on 2008-06-04 12:18:38 as read along with 1 group baker-group
  • Serine peptidases: Classification, structure and function
    Cellular and Molecular Life Sciences (CMLS)
    by M Page, E Di Cera
    posted to thrombin by sobolevnrm on 2008-03-31 12:30:30 as read
  • Structural identification of the pathway of long-range communication in an allosteric enzyme
    Proceedings of the National Academy of Sciences, Vol. 105, No. 6. (12 February 2008), pp. 1832-1837.
    by Prafull S Gandhi, Zhiwei Chen, Scott F Mathews, Enrico Di Cera
    posted to allostery structure thrombin by sobolevnrm on 2008-03-04 12:37:52 as read along with 2 people and 1 group lna cactus baker-group
  • Thrombin
    Molecular Aspects of Medicine, Vol. In Press, Corrected Proof
    by Enrico Di Cera
    posted to thrombin review by sobolevnrm on 2008-04-29 11:26:25 as read along with 1 group baker-group
  • Mechanism of Na+ binding to thrombin resolved by ultra-rapid kinetics
    Biophysical Chemistry, Vol. In Press, Accepted Manuscript
    by Stefano Gianni, Ylva Ivarsson, Alaji Bah, Leslie A Bush-Pelc, Enrico Di Cera
    posted to thrombin by sobolevnrm on 2007-10-04 13:12:06 as read along with 1 group baker-group
  • Engineering Protein Allostery: 1.05 Å Resolution Structure and Enzymatic Properties of a Na+-activated Trypsin
    Journal of Molecular Biology, Vol. 378, No. 3. (2 May 2008), pp. 666-672.
    by Michael J Page, Christopher J Carrell, Enrico Di Cera
    posted to thrombin protein-ligand_interactions protein_engineering allostery by sobolevnrm on 2008-05-03 12:32:51 as read along with 1 group baker-group
  • Triggers, targets and treatments for thrombosis
    Nature, Vol. 451, No. 7181. (21 February 2008), pp. 914-918.
    by Nigel Mackman
    posted to thrombin by sobolevnrm on 2008-03-14 11:14:39 as read along with 1 person and 1 group DavidG67 baker-group
  • Molecular dynamics simulation of ion selectivity process in nanopores
    Molecular Simulation, Vol. 34, No. 2. (2008), pp. 169-175.
    by Hongmei Liu, Cynthia J Jameson, Sohail Murad
    posted to thrombin solvation electrostatics by sobolevnrm on 2008-06-17 11:59:39 as read along with 1 group baker-group
  • Signaling during lens regeneration.
    Semin Cell Dev Biol, Vol. 17, No. 6. (December 2006), pp. 753-758.
    by MW Grogg, MK Call, PA Tsonis
    posted to bmp fgf lens newt pax-6 regeneration review signaling six-3 thrombin by lisa1 on 2007-05-07 23:16:54 as ***
  • In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits.
    Blood, Vol. 81, No. 12. (15 June 1993), pp. 3271-3276.
    by LC Griffin, GF Tidmarsh, LC Bock, JJ Toole, LL Leung
    posted to thrombin by gruppo on 2007-07-10 14:46:33 as ** along with 1 person bpagano
  • Selection of single-stranded DNA molecules that bind and inhibit human thrombin.
    Nature, Vol. 355, No. 6360. (6 February 1992), pp. 564-566.
    by LC Bock, LC Griffin, JA Latham, EH Vermaas, JJ Toole
    posted to thrombin by gruppo on 2007-07-10 14:45:27 as ** along with 1 person leelarcombe
  • A player of many parts: the spotlight falls on thrombin's structure.
    Thromb Res, Vol. 69, No. 1. (1 January 1993), pp. 1-58.
    by MT Stubbs, W Bode
    posted to thrombin by gruppo on 2007-07-10 14:27:14 as **
  • Molecular recognition mechanisms of thrombin
    Journal of Thrombosis and Haemostasis, Vol. 3, No. 8. (August 2005), pp. 1861-1872.
    by JA Huntington
    posted to thrombin by gruppo on 2007-07-10 14:26:15 as **
  • The coagulation cascade: initiation, maintenance, and regulation.
    Biochemistry, Vol. 30, No. 43. (29 October 1991), pp. 10363-10370.
    by EW Davie, K Fujikawa, W Kisiel
    posted to thrombin by gruppo on 2007-07-10 14:22:56 as **
  • Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG).
    J Mol Biol, Vol. 256, No. 3. (1 March 1996), pp. 417-422.
    by JA Kelly, J Feigon, TO Yeates
    posted to thrombin by gruppo on 2007-07-10 14:54:38 as **
  • A new modified thrombin binding aptamer containing a 55 inversion of polarity site
    Nucleic Acids Research, Vol. 34, No. 22. (December 2006), pp. 6653-6662.
    by Martino, Luigi, Virno, Ada, Randazzo, Antonio, Virgilio, Antonella, Esposito, Veronica, Giancola, Concetta, Bucci, Mariarosaria, Cirino, Giuseppe, Mayol, Luciano
    posted to thrombin by gruppo on 2007-07-10 14:52:40 as ** along with 1 person and 2 groups jmrivort G-quadruplex Supramolecular
  • The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.
    J Biol Chem, Vol. 268, No. 24. (25 August 1993), pp. 17651-17654.
    by K Padmanabhan, KP Padmanabhan, JD Ferrara, JE Sadler, A Tulinsky
    posted to thrombin by gruppo on 2007-07-10 14:52:00 as **
  • An ambiguous structure of a DNA 15-mer thrombin complex.
    Acta Crystallogr D Biol Crystallogr, Vol. 52, No. Pt 2. (1 March 1996), pp. 272-282.
    by K Padmanabhan, A Tulinsky
    posted to thrombin by gruppo on 2007-07-10 14:50:55 as **
  • Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution.
    Proc Natl Acad Sci U S A, Vol. 90, No. 8. (15 April 1993), pp. 3745-3749.
    by RF Macaya, P Schultze, FW Smith, JA Roe, J Feigon
    posted to thrombin by gruppo on 2007-07-10 14:49:24 as **
  • A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA.
    Biochemistry, Vol. 32, No. 8. (2 March 1993), pp. 1899-1904.
    by KY Wang, S McCurdy, RG Shea, S Swaminathan, PH Bolton
    posted to thrombin by gruppo on 2007-07-10 14:48:30 as **
  • A novel nucleotide-based thrombin inhibitor inhibits clot-bound thrombin and reduces arterial platelet thrombus formation.
    Blood, Vol. 83, No. 3. (1 February 1994), pp. 677-682.
    by WX Li, AV Kaplan, GW Grant, JJ Toole, LL Leung
    posted to thrombin by gruppo on 2007-07-10 14:47:27 as ** along with 1 person bpagano
  • AMBER, a package of computer programs for applying molecular mechanics, normal mode analysis, molecular dynamics and free energy calculations to simulate the structural and energetic properties of molecules
    Computer Physics Communications, Vol. 91, No. 1-3. (2 September 1995), pp. 1-41.
    by David A Pearlman, David A Case, James W Caldwell, Wilson S Ross, Iii Cheatham, Steve Debolt, David Ferguson, George Seibel, Peter Kollman
    posted to thrombin by gruppo on 2007-07-10 16:28:37 as ** along with 1 person papatonyhill
  • A modified version of the Cornell et al. force field with improved sugar pucker phases and helical repeat.
    J Biomol Struct Dyn, Vol. 16, No. 4. (February 1999), pp. 845-862.
    by TE Cheatham, P Cieplak, PA Kollman
    posted to thrombin by gruppo on 2007-07-10 15:35:47 as ** along with 2 people lillekatt ffranca
  • ZDOCK: an initial-stage protein-docking algorithm.
    Proteins, Vol. 52, No. 1. (1 July 2003), pp. 80-87.
    by R Chen, L Li, Z Weng
    posted to thrombin by gruppo on 2007-07-10 15:26:40 as ** along with 4 people and 2 groups jwm bicko ffranca selrac Radiation_Damage Stressosome
  • The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids.
    J Biomol Struct Dyn, Vol. 6, No. 1. (August 1988), pp. 63-91.
    by R Lavery, H Sklenar
    posted to thrombin by gruppo on 2007-07-10 15:20:15 as **
  • Effect of loop sequence and size on DNA aptamer stability.
    Biochemistry, Vol. 39, No. 6. (15 February 2000), pp. 1462-1468.
    by I Smirnov, RH Shafer
    posted to thrombin by gruppo on 2007-07-10 15:17:24 as ** along with 1 person luigi
  • Unfolding of G-quadruplexes: energetic, and ion and water contributions of G-quartet stacking.
    J Phys Chem B Condens Matter Mater Surf Interfaces Biophys, Vol. 110, No. 13. (6 April 2006), pp. 6962-6969.
    by CM Olsen, WH Gmeiner, LA Marky
    posted to thrombin by gruppo on 2007-07-10 15:15:45 as **
  • Prediction of MEF2A-DNA interface by rigid body docking: a tool for fast estimation of protein mutational effects on DNA binding.
    J Struct Biol, Vol. 153, No. 3. (March 2006), pp. 278-283.
    by F Fanelli, S Ferrari
    posted to thrombin by gruppo on 2007-07-10 15:12:19 as **
  • The single-stranded DNA aptamer-binding site of human thrombin.
    J Biol Chem, Vol. 268, No. 28. (5 October 1993), pp. 20808-20811.
    by LR Paborsky, SN McCurdy, LC Griffin, JJ Toole, LL Leung
    posted to thrombin by gruppo on 2007-07-10 15:10:05 as **
  • The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity.
    Biochemistry, Vol. 32, No. 42. (26 October 1993), pp. 11285-11292.
    by KY Wang, SH Krawczyk, N Bischofberger, S Swaminathan, PH Bolton
    posted to thrombin by gruppo on 2007-07-10 15:09:20 as **
  • Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite.
    J Biol Chem, Vol. 267, No. 34. (5 December 1992), pp. 24408-24412.
    by Q Wu, M Tsiang, JE Sadler
    posted to thrombin by gruppo on 2007-07-10 15:08:40 as **
  • Functional mapping of the surface residues of human thrombin.
    J Biol Chem, Vol. 270, No. 28. (14 July 1995), pp. 16854-16863.
    by M Tsiang, AK Jain, KE Dunn, ME Rojas, LL Leung, CS Gibbs
    posted to thrombin by gruppo on 2007-07-10 15:07:46 as **
  • Selection of a suppressor mutation that restores affinity of an oligonucleotide inhibitor for thrombin using in vitro genetics.
    J Biol Chem, Vol. 270, No. 33. (18 August 1995), pp. 19370-19376.
    by M Tsiang, CS Gibbs, LC Griffin, KE Dunn, LL Leung
    posted to thrombin by gruppo on 2007-07-10 15:07:28 as **
  • Platelet PAR1 receptor density--Correlation to platelet activation response and changes in exposure after platelet activation
    Thrombosis Research, Vol. In Press, Corrected Proof
    by Sofia Ramstrom, Karin V Oberg, Finn Akerstrom, Camilla Enstrom, Tomas L Lindahl
    posted to cytometry flow par1 platelets receptor thrombin trap by DavidG67 on 2007-11-29 16:57:38 as ****
  • Preconditioning of primary human endothelial cells with inflammatory mediators alters the "set point" of the cell.
    FASEB J, Vol. 19, No. 13. (November 2005), pp. 1914-1916.
    by Y Wada, H Otu, S Wu, MR Abid, H Okada, T Libermann, T Kodama, SC Shih, T Minami, WC Aird
    posted to endothelium huvec inflammation nf-kb sepsis thrombin by 7ofAnn on 2007-05-14 11:10:39 as ***
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