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タグ: cxcr4 [111 articles]

Recent papers classified by the tag cxcr4.
  • Nef Proteins from Diverse Groups of Primate Lentiviruses Downmodulate CXCR4 To Inhibit Migration to the Chemokine Stromal Derived Factor 1
    J. Virol., Vol. 79, No. 16. (15 August 2005), pp. 10650-10659.
    by Kasia Hrecka, Tomek Swigut, Michael Schindler, Frank Kirchhoff, Jacek Skowronski
    posted to cxcr4 nef by zukeboy on 2005-12-13 06:50:39 as **
  • Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury
    Kidney International, Vol. 67, No. 5. (May 2005), pp. 1772-1784.
    by Florian Togel, Jorge Isaac, Zhuma Hu, Kathy Weiss, Christof Westenfelder
    posted to chemokine cxcr4 homing ischemiareperfusion kidney sdf-1 by yavanna on 2008-01-15 01:40:58 as *****
  • Mycobacterium tuberculosis upregulates coreceptors CCR5 and CXCR4 while HIV modulates CD14 favoring concurrent infection.
    AIDS Res Hum Retroviruses, Vol. 22, No. 1. (January 2006), pp. 45-51.
  • Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells.
    Stem Cells, Vol. 22, No. 6. (2004), pp. 1015-1029.
    posted to cxcr4 trafficking by tkershaw on 2005-11-04 17:06:28 as ****
  • Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells.
    Cancer Res, Vol. 66, No. 11. (1 June 2006), pp. 5665-5675.
    by Y Ueda, NF Neel, E Schutyser, D Raman, A Richmond
    posted to chemotaxis cxcr4 by tkershaw on 2006-07-31 09:28:45 as ** along with 2 people cgmill01 vmsr
  • Functional expression of the C-X-C chemokine receptor CXCR4 by human bronchial epithelial cells: regulation by proinflammatory mediators.
    Journal of immunology (Baltimore, Md. : 1950), Vol. 169, No. 11. (1 December 2002), pp. 6445-6451.
    posted to chemokine cxcr4 by tkershaw on 2008-07-16 14:57:27 as **
  • Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?
    Journal of virology, Vol. 73, No. 4. (April 1999), pp. 3443-3448.
    by YJ Zhang, JP Moore
    posted to ccr5 cxcr4 intro by tkershaw on 2008-06-07 11:36:47 as **
  • Down-regulation of cell surface CXCR4 by HIV-1
    Virology Journal, Vol. 5 (11 January 2008), 6.
    by Bongkun Choi, Paul J Gatti, Cesar D Fermin, Sandor Vigh, Allyson M Haislip, Robert F Garry
    posted to cxcr4 endocytosis hiv by tkershaw on 2008-01-16 09:20:57 as **
  • Regulation of CXCR4 signaling
    Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1768, No. 4. (April 2007), pp. 952-963.
    by John M Busillo, Jeffrey L Benovic
    posted to benovic cxcr4 review by tkershaw on 2007-06-04 09:14:43 as **
  • The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4.
    Dev Cell, Vol. 5, No. 5. (November 2003), pp. 709-722.
    posted to cxcr4 trafficking ubiquitin by tkershaw on 2005-11-04 16:58:20 as read
  • The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1.
    Nature, Vol. 382, No. 6594. (29 August 1996), pp. 833-835.
    posted to cxcr4 by tkershaw on 2005-11-15 13:15:42 as **
  • Chemokine receptors.
    Cytokine Growth Factor Rev, Vol. 12, No. 4. (December 2001), pp. 313-335.
    by R Horuk
    posted to ccr5 chemokine_receptor cxcr4 review by tkershaw on 2005-10-18 10:41:38 as read
  • HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor.
    Science (New York, N.Y.), Vol. 272, No. 5263. (10 May 1996), pp. 872-877.
    by Y Feng, CC Broder, PE Kennedy, EA Berger
    posted to cxcr4 hiv by tkershaw on 2008-07-18 12:47:36 as **
  • Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4.
    Mol Biol Cell, Vol. 14, No. 8. (August 2003), pp. 3305-3324.
    by S Venkatesan, JJ Rose, R Lodge, PM Murphy, JF Foley
    posted to ccr5 cxcr4 ptm trafficking by tkershaw on 2005-11-04 17:07:36 as read
  • Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting
    J. Biol. Chem., Vol. 276, No. 49. (30 November 2001), pp. 45509-45512.
    by Adriano Marchese, Jeffrey L Benovic
    posted to cxcr4 by tkershaw on 2008-06-06 21:57:34 as ** along with 1 person SaoriShimizu
  • HIV-1 gp120 chemokine receptor-mediated signaling in human macrophages.
    Immunol Res, Vol. 27, No. 2-3. (2003), pp. 261-276.
    by BD Freedman, QH Liu, M Del Corno, RG Collman
    posted to ccr5 collman cxcr4 review by tkershaw on 2005-11-18 16:48:02 as **
  • beta -Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This Implicates Multiple Interaction Sites between beta -Arrestin and CXCR4
    J. Biol. Chem., Vol. 275, No. 4. (28 January 2000), pp. 2479-2485.
    by Zhi-Jie Cheng, Jian Zhao, Yue Sun, Wei Hu, Ya-Lan Wu, Bo Cen, Guo-Xiang Wu, Gang Pei
    posted to cxcr4 by tkershaw on 2008-07-31 12:02:10 as **
  • What's New in HIV/AIDS? Chemokine Receptor Antagonists: A New Era of HIV Therapy?
    Infection, Vol. 33, No. 5-6. (October 2005), pp. 408-410.
    by B Jülg, FD Goebel
    posted to ccr5 cxcr4 hiv therapy by tkershaw on 2005-11-02 09:39:55 as read
  • Chemokine receptor 4 (CXCR4) is part of the lipopolysaccharide "sensing apparatus"
    Eur J Immunol (14 December 2007)
    by Martha Triantafilou, Philipp M M Lepper, Caspar David D Briault, Mohamed Abd Elrahman A Ahmed, Josh M M Dmochowski, Christian Schumann, Kathy Triantafilou
    posted to cxcr4 by tkershaw on 2007-12-19 09:21:39 as **
  • Arrestin-2 interacts with the E3 ubiquitin ligase AIP4 and mediates endosomal sorting of the chemokine receptor CXCR4.
    J Biol Chem (18 October 2007)
    by Deepali Bhandari, Joann Trejo, Jeffrey L L Benovic, Adriano Marchese
    posted to arrestin cxcr4 trafficking by tkershaw on 2007-10-22 09:46:01 as **
  • Chemokine receptors and HIV-1: the fusion of two major research fields.
    Immunol Today, Vol. 20, No. 2. (February 1999), pp. 89-94.
    by R Horuk
    posted to ccr5 chemokine_receptor cxcr4 hiv review by tkershaw on 2005-10-18 10:39:18 as read
  • Use of Inhibitors To Evaluate Coreceptor Usage by Simian and Simian/Human Immunodeficiency Viruses and Human Immunodeficiency Virus Type 2 in Primary Cells
    J. Virol., Vol. 74, No. 15. (1 August 2000), pp. 6893-6910.
    by Yi-Jun Zhang, Bernard Lou, Renu B Lal, Agegnehu Gettie, Preston A Marx, John P Moore
    posted to ccr5 cxcr4 hiv intro by tkershaw on 2008-06-07 11:38:12 as **
  • Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation.
    J Biol Chem, Vol. 277, No. 51. (20 December 2002), pp. 49212-49219.
    by Y Sun, Z Cheng, L Ma, G Pei
    posted to arrestin chemokine_receptor chemotaxis cxcr4 signalling by tkershaw on 2006-07-18 14:25:02 as **
  • Development of Anti-HIV Agents Targeting Dynamic Supramolecular Mechanism: Entry and Fusion Inhibitors Based on CXCR4/CCR5 Antagonists and gp41-C34-Remodeling Peptides.
    Curr HIV Res, Vol. 3, No. 4. (October 2005), pp. 289-301.
    by H Tamamura, A Otaka, N Fujii
    posted to ccr5 cxcr4 hiv therapy by tkershaw on 2005-10-31 09:15:22 as read
  • Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1alpha
    J Cell Sci (27 February 2007)
    by Mercedes Rey, Agustín Valenzuela-Fernández, Ana Urzainqui, María Yáñez-Mó, Manuel Pérez-Martínez, Petronila Penela, Federico Mayor Jr, Francisco Sánchez-Madrid
    posted to cxcr4 endocytosis by tkershaw on 2007-03-05 09:00:21 as **
  • Control of Chemokine-Guided Cell Migration by Ligand Sequestration
    Cell, Vol. 132, No. 3. (8 February 2008), pp. 463-473.
    by Bijan Boldajipour, Harsha Mahabaleshwar, Elena Kardash, Michal Reichman-Fried, Heiko Blaser, Sofia Minina, Duncan Wilson, Qiling Xu, Erez Raz
    posted to chemotaxis cxcr4 by tkershaw on 2008-03-13 09:12:44 as **
  • The HIV entry inhibitors revisited.
    Curr Med Chem, Vol. 13, No. 8. (2006), pp. 911-934.
    by JT Leonard, K Roy
    posted to ccr5 cxcr4 hiv review therapy by tkershaw on 2006-04-18 08:59:34 as **
  • HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication.
    J Exp Med, Vol. 186, No. 1. (7 July 1997), pp. 139-146.
    posted to cxcr4 by tkershaw on 2005-11-15 13:16:46 as **
  • Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.
    J Biol Chem, Vol. 274, No. 43. (22 October 1999), pp. 31076-31086.
    by MJ Orsini, JL Parent, SJ Mundell, JL Benovic, A Marchese
    posted to cxcr4 by tkershaw on 2005-11-15 13:35:14 as **
  • HIV and the chemokine system: 10 years later
    The EMBO Journal, Vol. aop, No. current. (26 January 2006)
    by Paolo Lusso
    posted to ccr5 cxcr4 hiv review by tkershaw on 2006-01-30 08:52:56 as ** along with 1 person gokhan
  • Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.
    J Cell Biol, Vol. 139, No. 3. (3 November 1997), pp. 651-664.
    posted to cxcr4 nath by tkershaw on 2005-10-17 10:38:45 as read
  • Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling
    Blood, Vol. 101, No. 2. (15 January 2003), pp. 399-406.
    by Joachim Roland, Brendan J Murphy, Barbara Ahr, Veronique Robert-Hebmann, Vincent Delauzun, Keith E Nye, Christian Devaux, Martine Biard-Piechaczyk
    posted to chemotaxis cxcr4 by tkershaw on 2008-06-06 22:08:07 as **
  • The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry.
    Nature, Vol. 382, No. 6594. (29 August 1996), pp. 829-833.
    posted to cxcr4 by tkershaw on 2005-11-15 13:14:53 as **
  • The spreading of HIV-1 infection in the human organism is caused by fractalkine trafficking of the infected lymphocytes-a review, hypothesis and implications for treatment.
    Virus Genes (7 December 2006)
    by Yechiel Becker
    posted to ccr5 cxcr4 hiv review by tkershaw on 2006-12-12 09:21:06 as **
  • Bifurcation of Lipid and Protein Kinase Signals of PI3K to the Protein Kinases PKB and MAPK
    Science, Vol. 282, No. 5387. (9 October 1998), pp. 293-296.
    by Tzvetanka Bondeva, Luciano Pirola, Ginette Bulgarelli-Leva, Ignacio Rubio, Reinhard Wetzker, Matthias P Wymann
    posted to cxcr4 pi3k tcrmr by rhem1224 on 2006-06-23 09:28:49 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
    PNAS, Vol. 95, No. 16. (4 August 1998), pp. 9448-9453.
    by Qing Ma, Dan Jones, Paul R Borghesani, Rosalind A Segal, Takashi Nagasawa, Tadamitsu Kishimoto, Roderick T Bronson, Timothy A Springer
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:41:49 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • The alpha -Chemokine, Stromal Cell-derived Factor-1alpha , Binds to the Transmembrane G-protein-coupled CXCR-4 Receptor and Activates Multiple Signal Transduction Pathways
    J. Biol. Chem., Vol. 273, No. 36. (4 September 1998), pp. 23169-23175.
    by Ramesh K Ganju, Stephanie A Brubaker, Joshua Meyer, Parmesh Dutt, Yangming Yang, Shixin Qin, Walter Newman, Jerome E Groopman
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:33:54 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes.
    J Immunol, Vol. 163, No. 11. (1 December 1999), pp. 5954-5963.
    by Y Sotsios, GC Whittaker, J Westwick, SG Ward
  • Receptors induce chemotaxis by releasing the beta gamma subunit of Gi, not by activating Gq or Gs
    PNAS, Vol. 94, No. 26. (23 December 1997), pp. 14489-14494.
    by Enid R Neptune, Henry R Bourne
  • TCR activation inhibits chemotaxis toward stromal cell-derived factor-1: evidence for reciprocal regulation between CXCR4 and the TCR.
    J Immunol, Vol. 162, No. 1. (1 January 1999), pp. 215-223.
    by JW Peacock, FR Jirik
  • Src Tyrosine Kinase Is a Novel Direct Effector of G Proteins
    Cell, Vol. 102, No. 5. (1 September 2000), pp. 635-646.
    by Yong-Chao Ma, Jianyun Huang, Shariq Ali, William Lowry, Xin-Yun Huang
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:43:07 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • Identification of a Structural Element in Phospholipase C beta 2 That Interacts with G Protein beta gamma Subunits
    J. Biol. Chem., Vol. 273, No. 12. (20 March 1998), pp. 7148-7154.
    by Banumathi Sankaran, James Osterhout, Dianqing Wu, Alan V Smrcka
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:49:12 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gbeta[IMAGE]-mediated Mitogen-activated Protein Kinase Signaling Pathway
    J. Biol. Chem., Vol. 271, No. 21. (24 May 1996), pp. 12133-12136.
    by Brian E Hawes, Louis M Luttrell, Tim van Biesen, Robert J Lefkowitz
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:35:13 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • Roles of PLC-2 and -3 and PI3K in Chemoattractant-Mediated Signal Transduction
    Science, Vol. 287, No. 5455. (11 February 2000), pp. 1046-1049.
    by Zhong Li, Huiping Jiang, Wei Xie, Zuchuan Zhang, Alan V Smrcka, Dianqing Wu
  • Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase gamma
    Science, Vol. 275, No. 5298. (17 January 1997), pp. 394-397.
    by Marco Lopez-Ilasaca, Piero Crespo, Giuseppe P Pellici, Silvio J Gutkind, Reinhard Wetzker
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:40:18 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.
    J Exp Med, Vol. 192, No. 3. (7 August 2000), pp. 313-324.
  • Galpha i Is Not Required for Chemotaxis Mediated by Gi-coupled Receptors
    J. Biol. Chem., Vol. 274, No. 5. (29 January 1999), pp. 2824-2828.
    by Enid R Neptune, Taroh Iiri, Henry R Bourne
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:46:37 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • T Lymphocytes and Neutrophil Granulocytes Differ in Regulatory Signaling and Migratory Dynamics with Regard to Spontaneous Locomotion and Chemotaxis
    Cellular Immunology, Vol. 199, No. 2. (1 February 2000), pp. 104-114.
    by Frank Entschladen, Matthias Gunzer, Chi M Scheuffele, Bernd Niggemann, Kurt S Zanker
    posted to cxcr4 tcrmr by rhem1224 on 2006-06-23 09:31:03 as ** along with 2 groups TCR_Signaling SysbioMPI-TCells
  • Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.
    Blood, Vol. 106, No. 5. (1 September 2005), pp. 1824-1830.
    by M Burger, T Hartmann, M Krome, J Rawluk, H Tamamura, N Fujii, TJ Kipps, JA Burger
    posted to b-cll cd184 cll cxcl12 cxcr4 by philill on 2006-11-03 09:08:51 as ***
  • CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease.
    Ann Hematol, Vol. 82, No. 8. (August 2003), pp. 500-505.
    posted to b-cll cxcr4 sdf1 by philill on 2006-11-17 20:49:28 as **
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