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タグ: compound [29 articles]

Recent papers classified by the tag compound.
  • From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries.
    Angew Chem Int Ed Engl, Vol. 41, No. 16. (16 August 2002), pp. 2879-2890.
    posted to compound domain drug by tny on 2006-12-06 11:26:18 as ** along with 1 person jerome_ucsf_slb
  • Principles of Two-Photon Excitation Microscopy and Its Applications to Neuroscience
    Neuron, Vol. 50, No. 6. (June 2006), pp. 823-839.
    by Karel Svoboda, Ryohei Yasuda
  • Bootstrap-based consensus scoring method for protein-ligand docking.
    Journal of chemical information and modeling, Vol. 48, No. 5. (May 2008), pp. 988-996.
    posted to small scoring function docking compound by reyez on 2008-07-15 10:05:50 as **
  • Homology Model-Based Virtual Screening for GPCR Ligands Using Docking and Target-Biased Scoring
    J. Chem. Inf. Model., Vol. 48, No. 5. (27 May 2008), pp. 1104-1117.
    by Sebastian, Tanja Weil, Steffen Renner
    posted to small screening like gpcr drug docking compound by reyez on 2008-07-16 09:34:19 as **
  • Drug Target Identification Using Side-Effect Similarity
    Science, Vol. 321, No. 5886. (11 July 2008), pp. 263-266.
    by Monica Campillos, Michael Kuhn, Anne-Claude Gavin, Lars J Jensen, Peer Bork
  • Chemical complementation: small-molecule-based genetic selection in yeast
    Biochemical and Biophysical Research Communications, Vol. 306, No. 3. (4 July 2003), pp. 774-780.
    by Bahareh Azizi, Eileen I Chang, Donald F Doyle
    posted to yeast rescue genetic defect compound by raiyar on 2007-01-11 12:40:34 as read along with 1 group steinmetzlab
  • An integrated platform of genomic assays reveals small-molecule bioactivities
    Nat Chem Biol, Vol. 4, No. 8. (2008), pp. 498-506.
    by Shawn Hoon, Smith, Iain M Wallace, Sundari Suresh, Molly Miranda, Eula Fung, Michael Proctor, Kevan M Shokat, Chao Zhang, Ronald W Davis, Guri Giaever, Robert P St Onge, Corey Nislow
  • Chemical complementation: a definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets.
    Pharmacol Ther, Vol. 107, No. 2. (August 2005), pp. 212-221.
    by A Vogt, JS Lazo
  • Mitochondrial targets of drug toxicity.
    Annu Rev Pharmacol Toxicol, Vol. 40 (2000), pp. 353-388.
    by KB Wallace, AA Starkov
    posted to review mitochondria compound by raiyar on 2007-01-19 11:42:17 as ** along with 1 group steinmetzlab
  • The impact of systems approaches on biological problems in drug discovery.
    Nature biotechnology, Vol. 22, No. 10. (October 2004), pp. 1215-1217.
    by L Hood, RM Perlmutter
    posted to systems review pharmacogen medicine ellstalk disease compound by raiyar on 2008-07-10 10:05:42 as read
  • Chemogenomic profiling: identifying the functional interactions of small molecules in yeast.
    Proc Natl Acad Sci U S A, Vol. 101, No. 3. (20 January 2004), pp. 793-798.
    by G Giaever, P Flaherty, J Kumm, M Proctor, C Nislow, DF Jaramillo, AM Chu, MI Jordan, AP Arkin, RW Davis
  • Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.
    Cell, Vol. 126, No. 3. (11 August 2006), pp. 611-625.
    by AB Parsons, A Lopez, IE Givoni, DE Williams, CA Gray, J Porter, G Chua, R Sopko, RL Brost, CH Ho, J Wang, T Ketela, C Brenner, JA Brill, GE Fernandez, TC Lorenz, GS Payne, S Ishihara, Y Ohya, B Andrews, TR Hughes, BJ Frey, TR Graham, RJ Andersen, C Boone
  • Genomic profiling of drug sensitivities via induced haploinsufficiency
    Nature Genetics, Vol. 21, No. 3. (March 1999), pp. 278-283.
    by G Giaever, DD Shoemaker, TW Jones, H Liang, EA Winzeler, A Astromoff, RW Davis
  • The genetic basis of variability in drug responses
    Nat Rev Drug Discov, Vol. 1, No. 1. (January 2002), pp. 37-44.
    by Dan M Roden, Alfred L George
    posted to variant review pharmacogen genetic ellstalk compound by raiyar on 2008-07-10 23:33:15 as **
  • Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes
    Cell, Vol. 116, No. 1. (9 January 2004), pp. 121-137.
    by Pek Y Lum, Christopher D Armour, Sergey B Stepaniants, Guy Cavet, Maria K Wolf, Scott J Butler, Jerald C Hinshaw, Philippe Garnier, Glenn D Prestwich, Amy Leonardson
  • Yeast models of human mitochondrial diseases: from molecular mechanisms to drug screening.
    Biotechnol J, Vol. 1, No. 3. (March 2006), pp. 270-281.
    posted to sgtcnih review projmt narp model mitochondria methodspaper disease compound by raiyar on 2008-01-21 10:33:47 as *****
  • Mitochondria as chi.
    Genetics, Vol. 179, No. 2. (June 2008), pp. 727-735.
    by DC Wallace
  • Exogenous manganous ion at millimolar levels rescues all known dioxygen-sensitive phenotypes of yeast lacking CuZnSOD.
    J Biol Inorg Chem, Vol. 10, No. 8. (December 2005), pp. 913-923.
    by RJ Sanchez, C Srinivasan, WH Munroe, MA Wallace, J Martins, TY Kao, K Le, EB Gralla, JS Valentine
  • Network analysis of FDA approved drugs and their targets.
    Mt Sinai J Med, Vol. 74, No. 1. (April 2007), pp. 27-32.
  • The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1.
    J Biol Chem, Vol. 280, No. 19. (13 May 2005), pp. 19078-19086.
    by A Vogt, A Tamewitz, J Skoko, RP Sikorski, KA Giuliano, JS Lazo
    posted to compound analysis by raiyar on 2007-01-15 16:27:23 as *** along with 1 group steinmetzlab
  • Revealing Complex Traits with Small Molecules and Naturally Recombinant Yeast Strains
    Chemistry & Biology, Vol. 13, No. 3. (March 2006), pp. 319-327.
    by Ethan O Perlstein, Douglas M Ruderfer, Gopal Ramachandran, Stephen J Haggarty, Leonid Kruglyak, Stuart L Schreiber
  • Simple word strings as compound keywords: an indexing and ranking method for Japanese texts
    (1993), pp. 227-236.
    by Yasushi Ogawa, Ayako Bessho, Masako Hirose
    posted to compound extraction indexing japanese keyword multilingual ranking by Phanix on 2006-04-02 08:16:48 as *****
  • Learning rules and their exceptions
    J. Mach. Learn. Res., Vol. 2 (2002), pp. 669-693.
    by Herv&\#233; D&\#233;jean
  • Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks
    Nature Biotechnology, Vol. 23, No. 3. (04 March 2005), pp. 377-383.
    by Diego d di Bernardo, Michael J Thompson, Timothy S Gardner, Sarah E Chobot, Erin L Eastwood, Andrew P Wojtovich, Sean J Elliott, Scott E Schaus, James J Collins
  • Extended Analysis of Motion-Compensated Frame Difference for Block-Based Motion Prediction Error
    IEEE Transactions on Image Processing, Vol. 16, No. 5. (May 2007), pp. 1232-1245.
    by KC Hui, WC Siu
  • Molecular basis of antifolate resistance
    Cancer and Metastasis Reviews, Vol. 26, No. 1. (March 2007), pp. 153-181.
    posted to folate dfhr compound by fpattyn to the group Neuroblastoma on 2008-06-04 10:14:24 as **
  • Visual Navigation of Compound Graphs
    by Marcus Raitner
    posted to graph compound by fonsissimo on 2008-06-11 09:30:03 as read
  • Novel approach to real-time flash photolysis and confocal [Ca2+] imaging
    Pflügers Archiv, Vol. 454, No. 4. (July 2007), pp. 663-673.
    posted to technique system spark npegta myocyte dye compound cardiac calcium caged by cherrie on 2008-07-23 10:21:36 as **
  • Activation of single cardiac and skeletal ryanodine receptor channels by flash photolysis of caged Ca2+.
    Biophys. J., Vol. 66, No. 6. (1 June 1994), pp. 1879-1886.
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