active active_site adaptability adaptation archaea_pol autoregulation backtracking bacteria binding biofilm bistability bsubtilis bursting catalysis_mechanism cell_division cell_fate cell_singalling chromatin chromosomes cleavage commentary competence complexity control control_theory criticality desicion_making development dna dnap dna-repair dna_replication ecoli elongation enzymes epigenetics error-correction error_rate evolution evolvability excitability experiment extrinsic eykaryotic fidelity fluctuations gene-circuits gene-expression gene-networks gene-regulation genome gre grea growth_rate hairpin-stabilised hierarchical hiv human information-theory initiation in-vivo kinetic_proofreading l-phage meiosis mrna mrnap multistability negative_feedback network-motifs networks netwrok news_and_views noise noise-frequency nucleosomes olfactory_genes organisation pause pauses perspective phenotype poissonian pol_ii polymerase population_density post-transcriptional potential promoter promoter-proximal proofreading quorum_sensing rate_reactions rearrangement regulation regulatory_network replication review rna rnai rnap robustness simulations single-cell single-molecule spectra sporulation srna stalling stochasticity stochastic_simulations structure synthetic-biology systems_biology tasep termination tfiis tfs theory toggle-switch topoisomerase traffic_model transcription transcription-factor translation uracil views vision yeast